Huabing, "Integrating remote sensing, GIS and dynamic models for landscape-level simulation of forest insect disturbance" (2017 Cellular automata (CA) is a powerful tool for modeling the evolution of macroscopic scale phenomena as it couples time, space, and variables together while remaining in a simplified form. However, such application has remained challenging in forest insect epidemics due to the highly dynamic nature of insect behavior. Recent advances in temporal trajectory-based image analysis offer an alternative way to obtain high-frequency model calibration data. In this study, we propose an insect-CA modeling framework that integrates cellular automata, remote sensing, and Geographic Information System to understand the insect ecological processes, and tested it with measured data of mountain pine beetle (MPB) in the Rocky Mountains. The overall accuracy of the predicted MPB mortality pattern in the test years ranged from 88% to 94%, which illuminates its effectiveness in modeling forest insect dynamics. We further conducted sensitivity analysis to examine responses of model performance to various parameter settings. In our case, the ensemble random forest algorithm outperforms the traditional linear regression in constructing the suitability surface. Small neighborhood size is more effective in simulating the MPB movement behavior, indicating that short-distance is the dominating dispersal mode of MPB. The introduction of a stochastic perturbation component did not improve the model performance after testing a broad range of randomness degree, reflecting a relative compact dispersal pattern rather than isolated outbreaks. We conclude that CA with remote sensing observation is useful for landscape insect movement analyses; however, consideration of several key parameters is critical in the modeling process and should be more thoroughly investigated in future work.