Continuum creep damage mechanics modelling of creep has been combined with the recently developed Monte Carlo simulations of precipitation kinetics in power plant ferritic steels. The precipitation simulation has been validated by applying it to a 9 wt-%Cr ferritic steel, P92 and using the microstructural data published in the literature. The microstructural evolution results of precipitation kinetics simulation are used in the continuum creep damage mechanics model to calculate the damage evolution instead of the model equations developed for specific creep damage. This approach has been applied to P92 to study the effects of different creep damage mechanisms on the creep behaviour. Reasonable agreement with experimental creep rupture data and creep curves has been obtained. The new approach shows promise to provide a useful tool for both new alloy development and component life prediction.