Modelling of tissue thermal injury formation process with application of direct sensitivity method

Jasiński, Marek

doi:10.15632/jtam-pl.52.4.947

Cited by 21 publications

(29 citation statements)

References 10 publications

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“…[14][15][16][17]). Differentiation of the Pennes equation with respect to the external heat transfer coefficient gives So, the sensitivity model can be created by the differentiation of ener boundary-initial conditions with respect to the parameter considered (a dire [14,15,16,17] …”

Section: Sensitivity Modelmentioning

confidence: 99%

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Sensitivity of transient temperature field in domain of forearm insulated by protective clothing with respect to perturbations of external boundary heat flux

Mochnacki

Ciesielski

2016

Bulletin of the Polish Academy of Sciences Technical Sciences

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Abstract. The problem discussed in the paper is numerical modeling of thermal processes in the domain of biological tissue secured by a layer of protective clothing being in thermal contact with the environment. The cross-section of the forearm (2D problem) is treated as non-homogeneous domain in which the sub-domains of skin tissue, fat, muscle and bone are distinguished. The air gap between skin tissue and protective clothing is taken into account. The process of external heating is determined by Robin boundary condition and sensitivity analysis with respect to the perturbations of heat transfer coefficient and ambient temperature is also discussed. Both the basic boundary-initial problem and the sensitivity problems are solved by means of control volume method using Voronoi polygons.

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Section: Sensitivity Modelmentioning

confidence: 99%

“…To obtain conditions (16) and (17) in the form analogous to Robin conditions (8) and (9), in the basic model one can write ( ) ( )…”

Section: U X T C U X T C G U X T E Tmentioning

confidence: 99%

Sensitivity of transient temperature field in domain of forearm insulated by protective clothing with respect to perturbations of external boundary heat flux

Mochnacki

Ciesielski

2016

Bulletin of the Polish Academy of Sciences Technical Sciences

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“…The transient heat transfer is described by the Pennes formulation in the form [3][4][5][6][7][8][9][10][11] , :…”

Section: Governing Equationsmentioning

confidence: 99%

“…is the volumetric specific heat of blood and T B corresponds to the artery temperature [3,7,12]. It is well known that biological tissues are characterized by a strong scattering and weak absorption in the so-called therapeutic window.…”

Section: Governing Equationsmentioning

confidence: 99%

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Modelling of thermal damage in laser irradiated tissue

Jasiński

2015

J. Appl. Math. Comput. Mech.

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Abstract. In the paper the numerical analysis of thermal processes proceeding in the 2D homogeneous biological tissue subjected to laser irradiation is presented. In particular, the influence of necrotic changes in tissue on the values of the perfusion coefficient and effective scattering coefficient are discussed. The transient heat transfer is described by the bioheat transfer equation in the Pennes formulation. As a model of light distribution in tissue, the first-order scattering approach has been used. At the stage of numerical realization the 1 st scheme of the boundary element method has been applied.

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Modeling of heat transfer distribution in tumor breast cancer during microwave ablation therapy

Selmi

Iqbal

Smida

et al. 2022

Micro & Optical Tech Letters

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Microwave (MW) ablation is a strong tool that has been used in clinical therapy for numerous cancer tumors. This method takes advantage of the heat from MW energy produced by an antenna to destroy cancer cells without causing damage to the healthy tissue. This technique's efficiency is correlated to the temperature reached during the MW process. The antenna immersed in a tissue radiates a power that heats the living tissue, that is, the cancer cells and their environment. The administered power leads to a temperature increase that should attain a particular level to enable the killing of the dangerous cancer cells. On the other hand, it should not exceed another level to preserve healthy cells. Bioheat and electromagnetic equations are used to model the thermal ablation process. The finite element method is used to solve the governing equations used to model the process. This article is devoted to studying the influence of the type of antenna on the temperature distribution in the breast tissue, the specific absorption rate (SAR), and the amount of the necrotic tissue. Two configurations have been investigated, namely, a singleor a double-slot antenna. The obtained results reveal that the temperature, SAR, and the fraction of necrotic of the breast tissue are higher when a singleslot antenna is used. In addition, the input MW power has an important effect on the results. Some precautions should be taken in advance to prevent the temperature from rising to 50°C, which may induce damage to healthy cells.

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Modelling of tissue thermal injury formation process with application of direct sensitivity method

Cited by 21 publications

References 10 publications

Sensitivity of transient temperature field in domain of forearm insulated by protective clothing with respect to perturbations of external boundary heat flux

Sensitivity of transient temperature field in domain of forearm insulated by protective clothing with respect to perturbations of external boundary heat flux

Modelling of thermal damage in laser irradiated tissue

Modeling of heat transfer distribution in tumor breast cancer during microwave ablation therapy

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