1974
DOI: 10.1021/ja00828a039
|View full text |Cite
|
Sign up to set email alerts
|

Models for chiral recognition in molecular complexation

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
32
0

Year Published

1979
1979
2016
2016

Publication Types

Select...
4
4
1

Relationship

0
9

Authors

Journals

citations
Cited by 113 publications
(32 citation statements)
references
References 4 publications
0
32
0
Order By: Relevance
“…8 Crown ethers, the most common of which have an 18-crown-6 unit, are primarily known for their ability to form host-guest complexes with and distinguish chiral primary amines. [9][10] The primary amine is analyzed as its protonated ammonium ion. The NH þ 3 unit forms three hydrogen bonds to oxygen atoms of the 18-crown-6 unit as shown in Figure 1a.…”
Section: Introductionmentioning
confidence: 99%
“…8 Crown ethers, the most common of which have an 18-crown-6 unit, are primarily known for their ability to form host-guest complexes with and distinguish chiral primary amines. [9][10] The primary amine is analyzed as its protonated ammonium ion. The NH þ 3 unit forms three hydrogen bonds to oxygen atoms of the 18-crown-6 unit as shown in Figure 1a.…”
Section: Introductionmentioning
confidence: 99%
“…NMR spectroscopy showed rapid host/guest association/dissociation rates at levels appropriate for efficient LC. 48 The chiral host was bonded to a styrenic-resin 49 or to a silica-gel support 50 through a ''leash'' attached to a naphthyl moiety, and used as a chiral bonded phase to separate racemic amines and amino acid esters, as their ammonium salts, under normal phase LC conditions. Another host of the 6-crown ether was prepared that contained a single bi-naphthyl moiety that was substituted in its 3,3Ј-positions with two -CH 2 OCH 2 CO 2 H ''arms.''…”
Section: Cram's Crown Ethersmentioning
confidence: 99%
“…This will cause different time-averaged solvation environments that may contribute to chiral recognition in the NMR spectrum. Chiral crown ethers have been an important group of host compounds for the enantiodiscrimination of protonated primary amines [6,7,8,9,10,11]. More recently, a chiral crown ether with a larger cavity was used for the chiral discrimination of secondary amines [12].…”
Section: Introductionmentioning
confidence: 99%