2020
DOI: 10.21103/article10(1)_ra1
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Modern Markers of Renal Damage in Diabetes Mellitus

Abstract: Diabetes mellitus (DM) is a public health problem worldwide. Despite the presence of various sugar-lowering drugs, correcting hyperglycemia and preventing late DM complications remain a difficult task. Unfortunately, DM complications are often detected at late stages, when there are irreversible changes and a global decrease in the function of damaged organs and systems. One of the most dangerous complications leading to early death of patients is diabetic nephropathy. However, the problem of finding early mar… Show more

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Cited by 2 publications
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“…In this regard, early detection of potentially reversible damage in the kidneys is critical. As a result, the elucidation of the mechanisms that contribute to these changes in the preclinical stages of DN, and their corresponding correction, remain topical issues that deserve the close attention of specialists [12][13][14].…”
Section: Introductionmentioning
confidence: 99%
“…In this regard, early detection of potentially reversible damage in the kidneys is critical. As a result, the elucidation of the mechanisms that contribute to these changes in the preclinical stages of DN, and their corresponding correction, remain topical issues that deserve the close attention of specialists [12][13][14].…”
Section: Introductionmentioning
confidence: 99%
“…По данной причине особенно актуальным становится выяснение механизмов, способствующих ранним изменениям почечных структур при СД. В данный момент выделены основные группы новых потенциальных почечных маркеров: тубулярные маркеры, маркеры повреждения подоцитов, факторы роста, иммуновоспалительные факторы, продукты обмена внеклеточного матрикса, позволяющие прогнозировать развитие ДН с высокой специфичностью и чувствительностью [8].…”
Section: Introductionunclassified