Objective: To determine in a series of randomized blinded
experiments using the REDEM technology whether differences
between high homeopathic potencies and similarly
potentized solvent can be detected. Design and Analysis:
A REDEM device was employed as a black box. Samples
were measured in a capacitor that was connected to 60 individual
oscillator circuits at frequencies between 250 and
930 KHz; their oscillation damping was recorded. In two experiments
(3 and 4 replications) stable differences between
a potentized ‘mother tincture’ and potentized solvent were
assessed. Statistical analysis was done using ANCOVA.
Results: Significant differences (p < 0.01) between remedy
and control were found, mostly at the same oscillator frequencies.
Those differences found for only one remedy always
were at frequencies adjacent to frequencies with differences
for other remedies. Visual analysis: Where output
curves were not near 0, remedy values were higher than
controls. Curves within a replication ran parallel, their distances
varied. Between replications, curve shapes and remedy-
control differences were similar, however, control
curves varied in height. Control and remedy curves between
experiments varied in shape. Effects increased with time
and sample conductivity. Ethanol 43% as solvent eliminated
the observed effects, use of polyethylene containers considerably
attenuated them. Conclusions: A probably physical
difference was seen between potentized homeopathic remedies
and potentized solvent. The differences are associated
with sample age, solvent, and container material. The
REDEM technology requires further investigation to determine
the nature of the underlying mechanisms of the observed
differences.