Modification of mucin clots by serum.

Interaction between hyaluronic acid and serum dispersed in collagen gels.

“…The following observations, made for a somewhat different purpose, may have some bearing on this matter. Some gross differences in mucin complexes from hyaluronic acid and fresh or heatinactivated serum proteins with acetic acid (Fraser and Harris, 1971) led us to examine reactions between hyaluronic acid and high concentrations of serum in less drastic conditions. We adopted the ingenious connective tissue model devised by Fessler (1960), who found that incorporation of synovial fluid in collagen gels greatly increased their resistance to compression by centrifugal force.…”