Modification on Ni-P Amorphous Catalyst with SiO2 and Pd

Abstract

Ni-P amorphous alloy is prepared by chemical reduction with hypophosphite and modified by introducing trace Pd to the alloy and depositing it on SiO2, which results in the great improvement on both the thermal stability and hydrogenation activity. The stabilizing effect of SiO2 and activating effect of Pd have been observed and discussed.

Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Mycobacterium Tuberculosis and Plasmodium Falciparum

“…Thus, the N-terminal Cbz group of 19 [24] wasc leaved by hydrogenation, allowing the free amine to be coupledw ith the N-Alloctryptophan derivativest ot he corresponding hexapeptides 23 a-e utilizing2 -bromo-1-ethyl-pyridiniumt etrafluoroborate (BEP). [52,53] Additional structurald iversity was introducedb y elongation to the heptapeptides eries 24 a-e and 27 a-e using either g,d-unsaturated amino acid derivative 14 or N-Alloc-l-Val-OH (26). To complete the synthesis, the methyl ester at the C-terminuswas saponified with lithium hydroxide.…”