2022
DOI: 10.17996/anc.22-00172
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Modified Algorithm Using Total Count for Calculating Myocardial Washout Rate in Single-Photon Emission Computerized Tomography

Abstract: Background:The arithmetic mean of washout rate (WR) (namely, AMWR) of each segment is a commonly used algorithm for calculating WR from a polar map in single-photon emission computerized tomography (SPECT). However, in this algorithm, uneven radiotracer uptake among segments affects WR calculation. To solve this possible issue, we formulated a modified algorithm for calculating WR based on the total count (namely, TCWR). Methods: The WR of iodine-123-β-methyl-p-iodophenylpentadecanoic acid (BMIPP) was calculat… Show more

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Cited by 4 publications
(2 citation statements)
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“…A long-axis image can be used as a reference for the selection of slice ranges, and a polar map display of WR is convenient for checking outlier WR values. One algorithm calculates WRs using average counts in early and late images, and another averages pixel-based WRs on polar maps ( 29 , 30 ). Although the results of the two methods generally agree when patients are defect-free, large metabolic defects and misaligned settings of the slice range could affect pixel-based average WRs.…”
Section: Quantitation Of Washout Ratesmentioning
confidence: 99%
See 1 more Smart Citation
“…A long-axis image can be used as a reference for the selection of slice ranges, and a polar map display of WR is convenient for checking outlier WR values. One algorithm calculates WRs using average counts in early and late images, and another averages pixel-based WRs on polar maps ( 29 , 30 ). Although the results of the two methods generally agree when patients are defect-free, large metabolic defects and misaligned settings of the slice range could affect pixel-based average WRs.…”
Section: Quantitation Of Washout Ratesmentioning
confidence: 99%
“…A significantly reduced 123 I-BMIPP WR is listed as essential in the TGCV diagnostic criteria 2020 of the Research and Development on Intractable Disease by the Japanese Ministry of Labour and Welfare ( 20 ), and clinical evidence has accumulated about the value of TGCV images ( 21 28 ). However, data acquisition, analysis, and display methods appropriate for quantifying 123 I-BMIPP WRs have not been sufficiently investigated ( 29 , 30 ). Therefore, this practice recommendation aimed to provide standard procedures for data acquisition and analysis for calculating 123 I-BMIPP clearance or washout from the heart.…”
Section: Introductionmentioning
confidence: 99%