Modified Bacterial Cellulose for Biomedical Applications

Tang, Karen Yuanting; Heng, Jerry Zhi Xiong; Chai, Casandra Hui Teng; Chan, Chui Yu; Low, Beverly Qian Ling; Chong, Serene Ming En; Loh, Hong Yi; Liu, Yupeng; Ye, Enyi; Loh, Xian Jun

doi:10.1002/asia.202200598

Cited by 10 publications

(4 citation statements)

References 132 publications

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“…Dressings with an antimicrobial load have attracted great interest in the field of wound healing due to site-specific distribution, reduced adverse effects, increased concentration at the target site, low incidence of resistance, and the use of agents not suitable for oral and systemic therapy [ 138 , 139 , 140 , 141 ]. Among them, BC membranes are well recognized and effective scaffolds for wound healing and have recently been reviewed in high detail [ 33 , 122 , 123 ].…”

Section: Biocide Formulations Of Bcmentioning

confidence: 99%

Bacterial Cellulose-Based Materials as Dressings for Wound Healing

et al. 2023

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Bacterial cellulose (BC) is produced by several microorganisms as extracellular structures and can be modified by various physicochemical and biological strategies to produce different cellulosic formats. The main advantages of BC for biomedical applications can be summarized thus: easy moldability, purification, and scalability; high biocompatibility; and straightforward tailoring. The presence of a high amount of free hydroxyl residues, linked with water and nanoporous morphology, makes BC polymer an ideal candidate for wound healing. In this frame, acute and chronic wounds, associated with prevalent pathologies, were addressed to find adequate therapeutic strategies. Hence, the main characteristics of different BC structures—such as membranes and films, fibrous and spheroidal, nanocrystals and nanofibers, and different BC blends, as well as recent advances in BC composites with alginate, collagen, chitosan, silk sericin, and some miscellaneous blends—are reported in detail. Moreover, the development of novel antimicrobial BC and drug delivery systems are discussed.

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Section: Biocide Formulations Of Bcmentioning

confidence: 99%

Bacterial Cellulose-Based Materials as Dressings for Wound Healing

et al. 2023

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“…The biocompatibility and functional characteristics of BC and xanthan are key factors promoting their application in biomedicine, e.g., tissue engineering, wound dressing, and drug delivery systems. Recently, many reviews describing the use of BC [7,37,[52][53][54][55][56][57][236][237][238][239][240][241][242] and xanthan [48,63,89,[243][244][245] in various fields have been published.…”

Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

“…This year, reviews by Qian et al (2023) and Jadczak et al (2023) summarized the state-of-the-art application of functional BCbased materials in biomedical fields [52,241]. Also, the recent review by Tang et al (2022) discussed some of the biomedical applications that use BC, including wound healing, drug delivery, tissue engineering, and tumor cell and cancer therapy [242]. The publications on using xanthan to obtain medical materials have appeared relatively recently.…”

Section: Applications Of Bc and Xanthanmentioning

confidence: 99%

Production of Bacterial Exopolysaccharides: Xanthan and Bacterial Cellulose

Revin,

Liyaskina,

Parchaykina

et al. 2023

IJMS

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Recently, degradable biopolymers have become increasingly important as potential environmentally friendly biomaterials, providing a wide range of applications in various fields. Bacterial exopolysaccharides (EPSs) are biomacromolecules, which due to their unique properties have found applications in biomedicine, foodstuff, textiles, cosmetics, petroleum, pharmaceuticals, nanoelectronics, and environmental remediation. One of the important commercial polysaccharides produced on an industrial scale is xanthan. In recent years, the range of its application has expanded significantly. Bacterial cellulose (BC) is another unique EPS with a rapidly increasing range of applications. Due to the great prospects for their practical application, the development of their highly efficient production remains an important task. The present review summarizes the strategies for the cost-effective production of such important biomacromolecules as xanthan and BC and demonstrates for the first time common approaches to their efficient production and to obtaining new functional materials for a wide range of applications, including wound healing, drug delivery, tissue engineering, environmental remediation, nanoelectronics, and 3D bioprinting. In the end, we discuss present limitations of xanthan and BC production and the line of future research.

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“…Drug delivery, tissue engineering and other biomedical applications. [16] Alginate Alginate based biopolymers are widely applying for drug delivery, pharmaceutical and tissue engineering applications. [17] Hyaluronate Biomedical and pharmaceutical field.…”

Section: Cellulosementioning

confidence: 99%

Nanostructured Biopolymers for Biomedical Applications: A Review

Almasoudi¹,

Hussin²,

Alareeshi³

et al. 2022

Int. J. Res. Publ. Rev.

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Bio-based materials are considering as efficient, low cost and environmental friendly material for the different purposes including biomedical applications. Last few decades Nanostructured biopolymers have been widely used for several medical applications including wound heling, drug delivery, tissue engineering etc. as because of low cost, efficient and abundant presence of raw materials in around. This review was aimed to evaluate the role of nanostructured biopolymers for medical applications by the published works. The review also explored the efficiency, stability and mechanistic insight of different biopolymers for diverse medical applications by reported research published in the past.

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Modified Bacterial Cellulose for Biomedical Applications

Cited by 10 publications

References 132 publications

Bacterial Cellulose-Based Materials as Dressings for Wound Healing

Bacterial Cellulose-Based Materials as Dressings for Wound Healing

Production of Bacterial Exopolysaccharides: Xanthan and Bacterial Cellulose

Nanostructured Biopolymers for Biomedical Applications: A Review

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