Modulation of biochemical stress initiated by toxicants in diet prepared with fish smoked with polyethylene (plastic) materials as fuel source

Ujowundu, C. O.; Ogbede, J.U.; Igwe, K. O.; Nwaoguikpe, R. N.

doi:10.5897/ajb2015.15119

Cited by 4 publications

(3 citation statements)

References 57 publications

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“…Also, PAHs emission from motor vehicles and motorcycles are in the increase due to increased use of vehicles with old combustion technology and per capita increase in vehicle ownership. Furthermore, the consumption of charcoal broiled or smoked meats, fish, grains, and vegetable fats and oils (Yu, 2005;Ujowundu et al, 2014bUjowundu et al, , 2016, are sources of xenobiotic (especially PAHs) exposure.. Kidneys (and liver) are organs selectively targeted and injured by xenobiotics.…”

Section: Introductionmentioning

confidence: 99%

Biochemical and histological evaluation of benzo[a]pyrene induced nephrotoxicity and therapeutic potentials of Combretum zenkeri leaf extract

Ogbonna¹,

Ujowundu²,

Okwu³

et al. 2016

Afr. J. Pharm. Pharmacol.

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This study determined the therapeutic effect of ethanol leaf extract of Combretum zenkeri on kidney function of rats exposed to benzo[a]pyrene. Male Wistar albino rats were treated with ethanol leaf extract of C. zenkeri (400 mg/kg) in the presence or absence of BaP (200 mg/kg) for four weeks. The blood obtained at the end of the treatment was processed into serum and used for biochemical analyses and kidney tissues for histology. The serum creatinine, urea, sodium ion and potassium ion concentrations of the group exposed to benzo[a]pyrene without treatment with C. zenkeri extracts were significantly higher (p<0.05) as compared to the normal control group. The kidney histology indicated severely damaged glomeruli. The groups treated with the leaf extract pre-or post-benzo[a]pyrene exposure showed significant reduction (p<0.05) in serum concentration of urea, creatinine and sodium ion, while the pre-treated group showed no significant reduction (p<0.05) in serum potassium ion concentration. The biochemical and histological studies indicated that, C. zenkeri can ameliorate benzo[a]pyrene induced oxidative kidney damage.

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Section: Introductionmentioning

confidence: 99%

Biochemical and histological evaluation of benzo[a]pyrene induced nephrotoxicity and therapeutic potentials of Combretum zenkeri leaf extract

Ogbonna¹,

Ujowundu²,

Okwu³

et al. 2016

Afr. J. Pharm. Pharmacol.

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“…Iodine exists in various chemical forms, including iodine (I), iodate (IO₃⁻), and elemental iodine (I₂), with oxidation states of 5, -1, and 7. Iodine comprises thirty different isotopes, with 127I being the sole stable isotope occurring naturally [8,9].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Iodine and Goitrogens in Selected Vegetables from Owerri Imo State in Nigeria

Nwokocha

2024

Asian J. Biochem. Gen. Mol. Biol.

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The prevalence of iodine deficiency disorders remains a challenge in numerous developing nations despite widespread advocacy for iodized salt and iodine-fortified foods. As a result, this study assesses the iodine content of ten selected vegetables—water leaf, okra, green, tomatoes, lettuce, “okazi”, “ugu”, cabbage, “uha” leaf, and garden egg leaf. The result revealed varying iodine concentrations among these vegetables: 159.93±2.25 μg/kg for water leaf, 151.27±1.61 μg/kg for okra, and 160.43±4.37 μg/kg for green. Tomatoes exhibited 110.10±2.76 μg/kg, while lettuce had 181.27±1.76 μg/kg. “Okazi”, “ugu”, cabbage, “uha” leaf, and garden egg leaf showed iodine levels of 155.10±3.50 μg/kg, 153.43±2.47 μg/kg, 96.10±2.00 μg/kg, and 127.77±3.01 μg/kg, respectively. The evaluation for goitrogens demonstrated sufficient presence in these vegetables, with notable exceptions such as zinc, which was found in lower concentrations in “ugu”, lettuce, “okazi”, and cabbage, and was absent in “uha” leaf, garden egg leaf, green, water leaf, and okra. Based on these results, it was concluded that Owerri's vegetables exhibit relatively high iodine content within recommended dietary allowances. Consequently, ongoing vigilance is advised for the salt iodization program to prevent excess iodine intake, particularly among high-risk populations.

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“…The manufacture of plastic dates back to the 1950s. Since then, the sector has greatly grown and has become one of the biggest and most important sectors economically (Tudor et al, 2019). In fact, a world without plastics would actually seem unimaginable today (Geyer et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

A Review on the Role of Microbes in Polyethene Degradation

Okoth

Makonde

Bosire

et al. 2023

mjtum

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Polyethene is a polyolefin produced from polymerization of the olefin ethylene (C2H4). It is one of the most commonly used plastic and one of the most resistant to degradation. Its accumulation in the surrounding has caught the attention of many governments and researchers with attempts to come up with better disposal methods. This review focused on the role played by microorganisms in the degradation of polyethene. The references reviewed were obtained from journals and databases including PubMed, Google Scholar (http: //scholar. google.com) and Science Direct (http://www.science direct.com). We focused on data published from 2010 up to 2021. The findings obtained indicated that 19 genera of bacteria and actinomycetes and 5 fungal genera have the ability to degrade polyethene through secretion of extracellular depolymerases. The enzymes cleave polymer chains into low molecular weight fragments, which are then assimilated through the microbial cell membrane and mineralized. Microbial degradation is a sustainable and promising idea. However, there is need for more research to clearly determine the mechanism of enzymatic degradation, which will be useful in the development of novel biotechnological tools for degradation of a variety of plastic materials by microorganisms.

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Modulation of biochemical stress initiated by toxicants in diet prepared with fish smoked with polyethylene (plastic) materials as fuel source

Cited by 4 publications

References 57 publications

Biochemical and histological evaluation of benzo[a]pyrene induced nephrotoxicity and therapeutic potentials of Combretum zenkeri leaf extract

Biochemical and histological evaluation of benzo[a]pyrene induced nephrotoxicity and therapeutic potentials of Combretum zenkeri leaf extract

Evaluation of Iodine and Goitrogens in Selected Vegetables from Owerri Imo State in Nigeria

A Review on the Role of Microbes in Polyethene Degradation

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