2002
DOI: 10.1078/0944-7113-00093
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Modulatory effects of garlic extracts on proliferation of T-lymphocytes in vitro stimulated with concanavalin A

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Cited by 51 publications
(21 citation statements)
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“…In the determination of rutin activity on T-lymphocytes, rutin was found to suppress T-cell proliferation. During the T-cell proliferation, CD4+T-cell induce inflammatory cytokine secretion, which influences causing arthritis [37,38]. Thus, the suppression of the T-cell proliferation would be an important step in controlling arthritis.…”
Section: Discussionmentioning
confidence: 99%
“…In the determination of rutin activity on T-lymphocytes, rutin was found to suppress T-cell proliferation. During the T-cell proliferation, CD4+T-cell induce inflammatory cytokine secretion, which influences causing arthritis [37,38]. Thus, the suppression of the T-cell proliferation would be an important step in controlling arthritis.…”
Section: Discussionmentioning
confidence: 99%
“…The (R)-configuration at C(25) was confimed by the comparison of 1 H and 13 C resonances of HÀC(25), CH 2 (26), and Me (27) with data reported in the literature [6] [7]. In the HMBC spectrum ( Fig.…”
mentioning
confidence: 88%
“…In the traditional medicine, steroidal saponins isolated from different sources were shown to possess immunomodulatory activities, such as stimulation of lymphocyte proliferation [26], promotion of antibody production [27], and enhancement of phagocytic activity [28].…”
mentioning
confidence: 99%
“…Thymocytes and splenocytes were isolated as described by Colić et al (2002). Thymus and spleen were collected under aseptic conditions from BALB/c mice.…”
Section: Isolation Of Human Pbls Splenocytes and Thymocytes For Cellmentioning
confidence: 99%