Molar incisor hypomineralization: A review and prevalence in Japan

Saitoh, Masato; Shintani, Seikou

doi:10.1016/j.jdsr.2021.05.001

Cited by 10 publications

(11 citation statements)

References 65 publications

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“…Genetic factors affect all permanent teeth, not only primary teeth. Furthermore, permanent molar incisor hypomineralization (MIH), hypomineralized second primary molars (HSPM), and hypoplasia-associated severe early childhood caries are not genetic but the systemic factors of abnormal enamel formation [ 5 , 6 , 7 ]. Ameloblasts differentiate through the secretory, mineralization, and maturation stages for enamel formation.…”

Section: Introductionmentioning

confidence: 99%

The Retention Effect of Resin-Based Desensitizing Agents on Hypersensitivity—A Randomized Controlled Trial

et al. 2022

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Recently, the development of dental materials has increased the availability of various hyperesthesia desensitizers. However, there are no studies on the duration of retreatment in terms of adherence rates. Thus, the adhesion rates of resin-based desensitizers were investigated. We used a conventional desensitizer and a recently developed desensitizer containing calcium salt of 4-methacryloxyethyl trimellitic acid (C-MET) and 10-methacryloyloxydecyl dihydrogen calcium phosphate (MDCP). These colored agents were applied to the surfaces of premolars and molars, and the area was measured from weekly oral photographs. Areas were statistically analyzed and mean values were calculated using 95% confidence intervals. A p-value of <0.05 was considered statistically significant. These rates were significantly higher on the buccal side of the maxilla and lower on the lingual side of the maxilla. In addition, the desensitizer containing C-MET and MDCP displayed significantly higher adhesion rates. It is suggested that this will require monthly follow-ups and reevaluation because both agents cause less than 10% adherence and there is almost no sealing effect after 4 weeks. In addition, the significantly higher adhesion rate of the desensitizer containing C-MET and MDCP indicated that the novel monomer contributed to the improvement in the adhesion ability.

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Section: Introductionmentioning

confidence: 99%

The Retention Effect of Resin-Based Desensitizing Agents on Hypersensitivity—A Randomized Controlled Trial

et al. 2022

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“…Currently, it has been accepted that even premolars and canines might present opacities that share MIH characteristics, lower mineral and higher organic content (1). Hypomineralized teeth are more porous and susceptible to wear by masticatory forces and demineralization processes, such as dental caries (2,3). Although the etiology is not fully understood, genetic and environmental factors may be associated.…”

Section: Introductionmentioning

confidence: 99%

“…Although the etiology is not fully understood, genetic and environmental factors may be associated. In fact, MIH is a global concern in oral health and the prevalence of this condition can reach up to 44% (1,3,4).…”

Section: Introductionmentioning

confidence: 99%

“…Due to poor mineralization, MIH patients often require dental interventions, up to 10 times more than patients without the condition (2,3). The accelerated evolution of dental caries and the difficulties in establishing satisfactory restorative procedures (that require satisfactory adhesion to the dental substrate), together with difficulties in the cooperation of children in the dental office, make the clinical management of MIH patients a challenge in the dental settings.…”

Section: Introductionmentioning

confidence: 99%

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Case Report: Applicability of sedation with nitrous oxide in the management of molar incisor hypomineralization in pediatric patients

et al. 2022

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Patients with molar-incisor hypomineralization (MIH) may manifest tooth hfypersensitivity and difficulties in undergoing dental treatment, including fear, anxiety, and behavior problems in the dental office. Then, the objective of this study was to report a clinical case series using inhalation sedation with nitrous oxide and oxygen as a clinical strategy in the management of MIH pediatric patients during dental treatment. Pediatric patients and their legal guardians were properly informed and data were extracted from clinical charts. Six clinical cases were included, whose patients were between 8 and 12 years old. Of these, 4 were female. The indication of moderate sedation took into account the clinical difficulties related to patients with MIH, such as obtaining anesthesia and cooperation, in addition to odontophobia and dental anxiety. All patients were carefully examined to undergo the sedation technique, including medical history and previous experiences with nitrous oxide inhalation sedation, as well as the vital signs were properly evaluated before, during and after the procedures. The nitrous oxide concentration ranged between 30% and 60%. The procedures were restorative, endodontic or surgical (extractions). In general, the use of sedation contributed to the performance of dental procedures. The use of inhaled sedation helped in behavioral management and during the treatment, increasing the effectiveness of local anesthesia. Patients were cooperative for treatment, while no adverse effects or complications related to sedation were observed. Thus, for the patients in this case series, the use of inhalation sedation with nitrous oxide and oxygen contributed to the clinical management of patients with MIH.

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“…Permanent molar incisor hypomineralization (MIH), hypomineralized second primary molars (HSPM), and hypoplasia-associated severe early childhood caries (HAS-ECC) have recently been reported as systemic factors of amelogenesis imperfecta. The morbidity varies between countries, ranging from 2.8% to 36.5% [ 1 , 2 , 3 ]. Ameloblasts differentiate through secretory, mineralization and maturation stages to form enamel.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of a Hypersensitivity Inhibitor Containing a Novel Monomer That Induces Remineralization—A Case Series in Pediatric Patients

et al. 2021

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Background: Recently, tooth deformities have been frequently encountered by pediatric dentists. Severe enamel hypomineralization sometimes induces pain such as hyperesthesia, but composite resin restoration is difficult because it often detaches without any cavity preparation. Resin-based hypersensitivity inhibitors for tooth physically seal the dentinal tubules. It was reported that hypersensitivity inhibitor containing novel adhesive monomers forms apatite and induces remineralization in vitro. Therefore, these case series assessed the clinical effects of remineralization and the suppression of hypersensitivity by Bio Coat Ca (Sun Medical, Shiga, Japan). Methods: After mechanical tooth cleaning was performed, the hypersensitivity inhibitors were applied and cured by light exposure. Changes in hypersensitivity were determined by visual analog scale (VAS). The improvement of hypomineralization was evaluated by the change in color tone based on the digital images of intraoral photographs. Results: After repeated monthly treatments, these cases showed decreased hypersensitivity after the fourth application, while the opaque white and brownish color improved on the seventh application. Conclusion: This novel hypersensitivity inhibitor with calcium salt of 4-methacryloxyethyl trimellitic acid (C-MET) and 10-methacryloyloxydecyl dihydrogen calcium phosphate (MDCP) not only suppressed hypersensitivity but also improved cloudiness and brown spots in recently erupted permanent teeth in presented cases.

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Molar incisor hypomineralization: A review and prevalence in Japan

Cited by 10 publications

References 65 publications

The Retention Effect of Resin-Based Desensitizing Agents on Hypersensitivity—A Randomized Controlled Trial

The Retention Effect of Resin-Based Desensitizing Agents on Hypersensitivity—A Randomized Controlled Trial

Case Report: Applicability of sedation with nitrous oxide in the management of molar incisor hypomineralization in pediatric patients

Evaluation of a Hypersensitivity Inhibitor Containing a Novel Monomer That Induces Remineralization—A Case Series in Pediatric Patients

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