Molecular and genealogical analyses reveal multiple sources of the mutation associated with dermatosparaxis in Brazilian White Dorper sheep

Gouveia, João José de Simoni; Cunha, Samla Marques Freire; Almeida, Esdras Medeiros; Nogueira, Joel Fonseca; Filho, João Luiz Pereira Souza; Menezes, Daniel Ribeiro; Gouveia, Gisele Veneroni

doi:10.1016/j.smallrumres.2016.05.014

Cited by 2 publications

(1 citation statement)

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“…Rarely occurring genetic diseases may affect AW differently, depending on the type of disease. For example, complex vertebral malformation causes premature births, aborted fetuses, and stillborn calves in cattle (Wang et al ., 2011a, b), while dermatosparaxis leads to skin fragility and delayed wound healing in sheep (Gouveia et al ., 2016).…”

Section: Indirect Contributions Of Molecular Genetics To Fawmentioning

confidence: 99%

Direct and indirect contributions of molecular genetics to farm animal welfare: a review

Demir

Bilginer

Balcıoğlu

et al. 2021

Anim. Health. Res. Rev.

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Since domestication, farm animals have played a key role to increase the prosperity of humankind, while animal welfare (AW) is debated even today. This paper aims to comprehensively review the contributions of developing molecular genetics to farm animal welfare (FAW) and to raise awareness among both scientists and farmers about AW. Welfare is a complex trait affected by genetic structure and environmental factors. Therefore, the best welfare status can be achieved not only to enhance environmental factors such as management and feeding practices, but also the genetic structure of animals must be improved. In this regard, advances in molecular genetics have made great contributions to improve the genetic structure of farm animals, which has increased AW. Today, by sequencing and/or molecular markers, genetic diseases may be detected and eliminated in local herds. Additionally, genes related to diseases or adaptations are investigated by molecular techniques, and the frequencies of desired genotypes are increased in farm animals to keep welfare at an optimized level. Furthermore, stress on animals can be reduced with DNA extraction from stool and feather samples which reduces physical contact between animals and veterinarians. Together with molecular genetics, advances in genome editing tools and biotechnology are promising to improve FAW in the future.

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Section: Indirect Contributions Of Molecular Genetics To Fawmentioning

confidence: 99%