Molecular Biology of Chronic Myeloid Leukemia

Study of mesoporous magnesium carbonate in contact with whole human blood

“…While there is no doubt about the effect of Ca 2+ on the blood coagulation cascade, the description of the interactions of Mg 2+ with the proteins of the coagulation cascade has been more controversial. [33][34][35] Nevertheless, most of the studies indicate that Mg 2+ competes with Ca 2+ for clotting factors, resulting in an anticoagulant effect. 35 Having this in mind, the removal of Ca 2+ by Upsalite and the possible exchange with and/or release of Mg 2+ were explored in order to elucidate the mechanism behind the observed effect of Upsalite on the blood cascades.…”