Molecular characteristics, fitness, and virulence of high-risk and non-high-risk clones of carbapenemase-producing
Klebsiella pneumoniae
Anni-Maria Örmälä-Tiznado,
Lisa Allander,
Makaoui Maatallah
et al.
Abstract:Extensively drug-resistant (XDR)
Klebsiella pneumoniae
inflict a notable burden on healthcare worldwide. Of specific concern are strains producing carbapenem-hydrolyzing enzymes, as the therapeutic options for these strains are still very limited. Specific sequence types of
K. pneumoniae
have been noted for their epidemic occurrence globally, but the mechanisms behind the success of specific clones remain unclear. Herein, we have characterized 20 high-risk clones… Show more
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