Molecular characterization of lumpy skin disease virus in Namibia, 2017

Molini, Umberto; Aikukutu, Gottlieb; Khaiseb, Siegfried; Haindongo, Naindji N.; Lilungwe, Angela C.; Cattoli, Giovanni; Dundon, William G.; Lamien, Charles Euloge

doi:10.1007/s00705-018-3891-x

Cited by 17 publications

(12 citation statements)

References 8 publications

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“…In an endemic environment without other organized approaches to control the disease, farmers may simply perform vaccination as a stand-alone protection measure. For many areas in sub-Saharan Africa, this has been the reality over the past decades [ 98 , 99 , 100 ], highlighting the need to adapt vaccination strategies [ 101 ]. Facing localized LSD outbreaks, countries have opted for ring vaccinations of cattle and Asian water buffalo populations surrounding the outbreak(s) [ 7 , 98 ].…”

Section: The Role Of Vaccination In Lsd Prevention and Controlmentioning

confidence: 99%

Review: Vaccines and Vaccination against Lumpy Skin Disease

et al. 2021

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The geographical distribution of lumpy skin disease (LSD), an economically important cattle disease caused by a capripoxvirus, has reached an unprecedented extent. Vaccination is the only way to prevent the spread of the infection in endemic and newly affected regions. Yet, in the event of an outbreak, selection of the best vaccine is a major challenge for veterinary authorities and farmers. Decision makers need sound scientific information to support their decisions and subsequent actions. The available vaccine products vary in terms of quality, efficacy, safety, side effects, and price. The pros and cons of different types of live attenuated and inactivated vaccines, vaccination strategies, and associated risks are discussed. Seroconversion, which typically follows vaccination, places specific demands on the tools and methods used to evaluate the effectiveness of the LSD vaccination campaigns in the field. We aimed to give a comprehensive update on available vaccines and vaccination against LSD, to better prepare affected and at-risk countries to control LSD and ensure the safe trade of cattle.

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Section: The Role Of Vaccination In Lsd Prevention and Controlmentioning

confidence: 99%

Review: Vaccines and Vaccination against Lumpy Skin Disease

et al. 2021

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“…The invading LSDV was similar to those discovered in China in 2019, evidenced by our phylogenetic analyses. A few viral genomic regions, GPCR gene [ 20 , 22 ], ORF011, ORF012, ORF036 [ 16 ], P32 gene [ 21 ], and RPO30 gene [ 3 , 19 ], have been used in studying phylogeny of LSDV isolates. In the present study, GPCR, RPO30, and P32 genes were employed in generating phylogenetic trees ( Figs.…”

Section: Discussionmentioning

confidence: 99%

First detection and phylogenetic analysis of lumpy skin disease virus from Kinmen Island, Taiwan in 2020

Wang

et al. 2022

J. Vet. Med. Sci.

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Lumpy skin disease is an arthropod-borne bovine disease caused by lumpy skin disease virus. A suspect lumpy skin disease case in a breeding cattle farm on Kinmen Island, Taiwan was reported on July 8, 2020 and later confirmed the first occurrence of lumpy skin disease in the country by molecular biological detections, electron microscopy, and sequence comparison. Implementation of control measures including blanket vaccination on the island effectively ceased the outbreaks. Phylogenetic analyses revealed that the virus discovered in the outbreaks was most similar to those identified in China in 2019. Identifying this virus in the coastal areas in East Asia indicated the rapid eastward spread of lumpy skin disease in Asia.

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“…Although sequencing specific regions (e.g. RPO30 and GPCR) allows to discriminate vaccine from field strains, none of these regions contain sufficient information to study possible lines of transmission within an outbreak or epidemic ( Mafirakureva et al, 2017 ; Molini et al, 2018 ; Sudhakar et al, 2020 ). Comparison of the whole genome sequences of recent LSDV isolates from the 2015–2016 epidemic in southern Europe revealed only a limited number of point mutations between the isolates ( Agianniotaki et al, 2017 ; Mathijs et al, 2020b ,).…”

Section: Discussionmentioning

confidence: 99%