Molecular Fluorescence, Phosphorescence, and Chemiluminescence Spectrometry

Lowry, Mark; Fakayode, Sayo O.; Geng, M. Lei; Baker, Gary A.; Wang, Lin; McCarroll, Matthew E.; Patonay, Gábor; Warner, Isiah M.

doi:10.1021/ac800749v

Cited by 40 publications

(17 citation statements)

References 401 publications

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“…Traditionally, the investigation of CL phenomenon is limited to certain molecular systems with considerably strong CL emission [16]. Recently, in order to enhance the CL emission of traditional CL systems, or to explore novel CL systems, people have attempted to introduce nanomaterials into different CL systems, and some novel CL systems based on nanomaterials were developed.…”

Section: Introductionmentioning

confidence: 99%

A sensitive chemiluminescence method for the determination of cysteine based on silver nanoclusters

Wang

Xiang-nan

et al. 2012

Microchim Acta

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We have developed a sensitive chemiluminescent (CL) assay for cysteine. It is based on the use of watersoluble and fluorescent silver nanoclusters (Ag NCs) which are found to be able to strongly enhance the weak CL signal resulting from the redox reaction between Ce(IV) ion and sulfite ion. This enhancement is inhibited by cysteine under appropriate conditions. Taking advantage of this specific CL inhibition, a novel CL method for the sensitive and selective detection of cysteine was developed. This effect is interpreted in terms of an electronic energy transfer from excited state intermediate sulfur dioxide (originating from the CL reaction between Ce(IV) and sulfite ions) to the Ag-NCs. The latter become electronically excited and thus can act as a new source of emission. The method was applied to the determination of cysteine in the range from 5.0 nM to 1.0 μM, with a detection limit at 2.5 nM (S/N03).

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Section: Introductionmentioning

confidence: 99%

A sensitive chemiluminescence method for the determination of cysteine based on silver nanoclusters

Wang

Xiang-nan

et al. 2012

Microchim Acta

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“…Due to its convenient optical signal transduction, high sensitivity and rapid response ability, fluorescence-based sensing is currently by far the dominant analytical tool and is widely used in the field of chemical analysis, environmental monitoring and biological imaging [1,2]. Organic dyes are the most commonly used fluorescent labels, but their low absorption coefficients and weak signal lead to the reduced sensitivity and response of the targets.…”

Section: Introductionmentioning

confidence: 99%

Fluorescent nanoparticles for chemical and biological sensing

Liu

Yang

et al. 2011

Sci. China Chem.

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Fluorescent nanoparticles (NPs), including quantum dots (QDs), dye-doped NPs, and rare earth-based NPs, etc., have been a major focus of research and development during the past decade. The impetus behind such endeavors can be attributed to their unique chemical and optical properties, such as bright fluorescence, high photostability, large Stocks shift and flexible processability. The introduction of fluorescent NPs into analytical chemistry has opened up new venues for fluorescent analysis. In this review, we focus on the developments and analytical applications of fluorescent NPs in the chemical and biological sensing of pH, ions, organic compounds, small biological molecules, nucleic acids, proteins, virus and bacteria. The review also points out the in vitro and in vivo imaging application of fluorescent NPs at the cell and body levels. Meanwhile, the advantages of NPs brought field of sensing and signal transductions are also discussed. fluorescence, sensing, quantum dots, dye-doped nanoparticles, rare earth-based nanoparticles

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“…They have a high surface area, very small size (<20 nm) and high dispersion ability, spectrally selective coating [9, 10], surface-enhanced Raman scattering [11,12], and antibacterial activity [13]. Moreover, AgNPs exhibit optical properties which could not be observed either in molecular or in bulk metallic form [14][15][16][17].Fluorescence spectroscopy as a sensitive, simple, diverse, and nondestructive method can provide real time, in situ, and dynamic analytical information [18]. However, utilizing nanoparticles in fluorescence analysis has provided significant improvement in this area [19][20][21][22][23].…”

mentioning

confidence: 99%

“…Fluorescence spectroscopy as a sensitive, simple, diverse, and nondestructive method can provide real time, in situ, and dynamic analytical information [18]. However, utilizing nanoparticles in fluorescence analysis has provided significant improvement in this area [19][20][21][22][23].…”

mentioning

confidence: 99%

A nanosensor for determination of glucose based on silver nanoparticles as fluorescence probes

et al. 2015

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afforded by nanoscale technologies are expected to have substantial impacts on almost all industries and areas of society (e.g., medicine, plastics, energy, electronics, and aerospace) [1][2][3][4][5]. The recent advancement of bioanalytical techniques involving the development of highly sensitive or selective analytical methods based on nanoscale materials/molecules have progressed with remarkable success. In this regard, silver nanoparticles (AgNPs) have received significant attention in constructing analytical and bioanalytical sensors. This relevance arises from their unusual optical, electronic, and chemical properties [6][7][8]. They have a high surface area, very small size (<20 nm) and high dispersion ability, spectrally selective coating [9, 10], surface-enhanced Raman scattering [11,12], and antibacterial activity [13]. Moreover, AgNPs exhibit optical properties which could not be observed either in molecular or in bulk metallic form [14][15][16][17].Fluorescence spectroscopy as a sensitive, simple, diverse, and nondestructive method can provide real time, in situ, and dynamic analytical information [18]. However, utilizing nanoparticles in fluorescence analysis has provided significant improvement in this area [19][20][21][22][23]. It should be mentioned that the fluorescence of metal clusters and thin films is well established based on Mooradian's observation of photoluminescence from bulk copper and gold [24]. Also several reports are available related to the fluorescence of silver nanoclusters [25,26].Glucose, a simple sugar (monosaccharide), is an important carbohydrate in biology. Cells use it as a source of energy and a metabolic intermediate and its lack or excess can produce detrimental influence on cellular functions. The glucose level in blood is considered as a clinical indicator for diabetes. Therefore, the monitoring of glucose level in blood with faster and more accurate methods is in great demand and a great deal of effort has been focused Abstract A nanosensor was designed for the enzymatic determination of glucose based on the fluorescence enhancement of silver nanoparticles (AgNPs). This enhancement is the result of the glucose oxidase-catalyzed oxidation of glucose. Silver nanoparticles were prepared through a chemical reduction by using trisodium citrate as the reducing agent and were characterized with UV-visible spectroscopy, Fourier transform infrared spectroscopy and transmission electron microscopy. The experimental results showed that the increase of the AgNP fluorescence was linearly proportional to the concentration of glucose within its concentration ranges of 2.50 × 10 −5 -7.50 × 10 −3 M and 7.50 × 10 −3 -7.50 × 10 −2 M with a detection limit of 5.53 × 10 −7 M under the optimized experimental conditions. To evaluate the applicability of the nanobiosensor, determination of glucose in real samples was performed according to the developed procedure.

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Molecular Fluorescence, Phosphorescence, and Chemiluminescence Spectrometry

Cited by 40 publications

References 401 publications

A sensitive chemiluminescence method for the determination of cysteine based on silver nanoclusters

A sensitive chemiluminescence method for the determination of cysteine based on silver nanoclusters

Fluorescent nanoparticles for chemical and biological sensing

A nanosensor for determination of glucose based on silver nanoparticles as fluorescence probes

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