Molecular imprinting science and technology: a survey of the literature for the years 2004-2011

Abstract

SummaryHerein we present a survey of the literature covering the development of molecular imprinting science and technology over the years 2004 to 2011. In total, 3779 references to the original papers, reviews, edited volumes and monographs from this period are included, along with recently identified uncited materials from prior to 2004 which were omitted in the first instalment of this series covering the years 1930 to 2003. 1 In the presentation of the assembled references, a section presenting reviews and monographs covering the area is followed by sections describing fundamental aspects of molecular imprinting including the development of novel polymer formats. Thereafter, literature describing efforts to apply these polymeric materials to a range of application areas is presented. Current trends and areas of rapid development are discussed.2

Isotherm charts for material selection and method development with molecularly imprinted polymers and other sorbents

“…Molecularly imprinted polymers (MIPs) are selective sorbents [1][2][3][4]. Molecular imprinting involves arranging polymerizable functional monomers around a template molecule, followed by polymerization and template removal.…”

Molecular imprinted photonic crystal for sensing of biomolecules

“…In general terms, the approaches to molecular imprinting can be distinguished by the interaction between the template molecules and the functional monomers. They are covalent molecular imprinting, non-covalent molecular imprinting and metal-coordinating molecular imprinting [41][42].…”

Computational design of molecularly imprinted polymer for direct detection of melamine in milk

“…Additionally, high specificity and affinity in MIPs can be achieved by tailoring of their binding site at a molecular level. Although there are several formats of imprinting protocols available, by far the most popular method used in practice remains bulk imprinting, where solution containing template and monomers is polymerised to form a solid 'brick' which can then be broken, washed and used as the specific application requires such as the packing media of high performance liquid chromatography (HPLC) or solid phase extraction (SPE) columns or as the detection element of molecular sensors (2). Though it is the most tried and tested technique with a minimal number of interdependent steps, a notable challenge of the traditional molecular imprinting strategy of bulk imprinting can be seen when the molecular template selected has a low solubility in organic solvents.…”