2000
DOI: 10.1016/s0142-9612(00)00009-0
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Molecular mechanisms of improved adhesion and growth of an endothelial cell line cultured on polystyrene implanted with fluorine ions

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Cited by 66 publications
(30 citation statements)
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“…In their non-treated state, however, some materials usually form inadequate scaffolds for cell colonization, often due to their relatively high hydrophobicity (water drop contact angle in the range of about 90–120°). These materials can be rendered more hydrophilic by several techniques, particularly by irradiation with ultraviolet (UV) light [10], an ion beam [11,12,13] or exposure to plasma discharge [14,15,16]. In addition to the changes in surface wettability, these treatments also affect the roughness, morphology, electrical conductivity, stability, mechanical properties and chemical composition of the material surface.…”
Section: Introductionmentioning
confidence: 99%
“…In their non-treated state, however, some materials usually form inadequate scaffolds for cell colonization, often due to their relatively high hydrophobicity (water drop contact angle in the range of about 90–120°). These materials can be rendered more hydrophilic by several techniques, particularly by irradiation with ultraviolet (UV) light [10], an ion beam [11,12,13] or exposure to plasma discharge [14,15,16]. In addition to the changes in surface wettability, these treatments also affect the roughness, morphology, electrical conductivity, stability, mechanical properties and chemical composition of the material surface.…”
Section: Introductionmentioning
confidence: 99%
“…In construction of biocompatible artificial implants, one strategy aims at creation of materials promoting attachment, migration, proliferation, differentiation, long-term viability and cell functioning in a controllable manner, if possible. These materials can be constructed as surfaces colonized by cells, such as heart valves or vascular prostheses lined by contiguous, mature, naturally thromboresistant, nonimmunogenic and semipermeable endothelial layer [1][2][3], bone implants inducing formation of mineralized osseous tissue only at the interface of native tissue and artificial material [4], or skin substitutes containing polymeric sheet with a feeder layer of fibroblasts covered by keratinocytes [5].…”
Section: Introductionmentioning
confidence: 99%
“…14 that the absorbance of the modified samples was larger than that of the pristine magnesium substrate, suggesting that the growth and proliferation of endothelial cell on the modified magnesium surfaces were better than that of on the unmodiotein binding sites for cell attachment, the cells can grow well on the hydrophilic surface than that of on the hydrophobic magnesium surface. After alkali heating treatment and self-assembly, the surface hydrophilicity was enhanced and more chemical groups (such as -OH, -COOH, -NH 2 ) were introduced, thus cell adhesion can also occur through non-receptor chemical binding, such as electrostatic, ionic-polar interactions, hydrogen binding to surface functional groups [41,42], leading to the better proliferation. The substrate with the immobilized dopamine, APTMS and 3-phosphonopropionic acid can support initial cell adhesion and growth by forming hydrogen bonding with cells.…”
Section: Endothelial Cell Adhesion and Proliferationmentioning
confidence: 99%