2021
DOI: 10.1007/5584_2021_675
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Molecular Mechanisms of SARS-CoV-2/COVID-19 Pathogenicity on the Central Nervous System: Bridging Experimental Probes to Clinical Evidence and Therapeutic Interventions

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Cited by 2 publications
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“…
Many phenotypes have been described in the literature, the most named being the post-COVID 19 neurological syndrome, due to the findings of SARS-Cov-2 neurotropism and the process of active or passive neuroinflammation that can be generated during the acute phase of this disease, even in the absence of neurological symptoms. 3 Considering that the nervous system is very susceptible to injury and slow and unsafe recovery, it is one of the most serious phenotypes of attention. 3 Older patients with comorbidities have a higher risk of developing the severe COVID-19 phenotype, and in these patients, neuroplasticity is reduced due to age and microvascular injury from vascular enlargement and atherosclerosis.
…”
mentioning
confidence: 99%
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“…
Many phenotypes have been described in the literature, the most named being the post-COVID 19 neurological syndrome, due to the findings of SARS-Cov-2 neurotropism and the process of active or passive neuroinflammation that can be generated during the acute phase of this disease, even in the absence of neurological symptoms. 3 Considering that the nervous system is very susceptible to injury and slow and unsafe recovery, it is one of the most serious phenotypes of attention. 3 Older patients with comorbidities have a higher risk of developing the severe COVID-19 phenotype, and in these patients, neuroplasticity is reduced due to age and microvascular injury from vascular enlargement and atherosclerosis.
…”
mentioning
confidence: 99%
“…3 Older patients with comorbidities have a higher risk of developing the severe COVID-19 phenotype, and in these patients, neuroplasticity is reduced due to age and microvascular injury from vascular enlargement and atherosclerosis. 3 This leads us to think about the need to follow up on the neurological integrity of all patients who undergo a definitive diagnosis of COVID-19.…”
mentioning
confidence: 99%