Molecular phylogenetic reconstructions identify East Asia as the cradle for the evolution of the cosmopolitan genus Myotis (Mammalia, Chiroptera)

Rüedi, Manuel; Stadelmann, Benoît; Gager, Yann; Douzery, Emmanuel J. P.; Francis, Charles M.; Lin, Liang‐Kong; Guillén-Servent, Antonio; Cibois, Alice

doi:10.1016/j.ympev.2013.08.011

Cited by 143 publications

(153 citation statements)

References 61 publications

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“…The phlawd workflow first queries sequences from GenBank [19], compares the sequences to "known" gene segments of the taxa of interest and aligns the sequences based on the degree of relatedness depending on the degree of sequence saturation. We used five genes commonly sequenced for bats: One mitochondrial gene, CytB, two nuclear genes RAG2, Val, and two ribosomal genes, 12S, 16S [24][25][26]. The GenBank query returned 1024 taxonomic entries, and we removed entries with uncertain species identity or incomplete scientific names.…”

Section: Phylogenetic Tree Constructionmentioning

confidence: 99%

Predicting Extinction Risk for Data Deficient Bats

Welch

Beaulieu

2018

Diversity

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Conservation biology aims to identify species most at risk of extinction and to understand factors that forecast species vulnerability. The International Union for Conservation of Nature (IUCN) Red List is a leading source for extinction risk data of species globally, however, many potentially at risk species are not assessed by the IUCN owing to inadequate data. Of the approximately 1150 bat species (Chiroptera) recognized by the IUCN, 17 percent are categorized as Data Deficient. Here, we show that large trait databases in combination with a comprehensive phylogeny can identify which traits are important for assessing extinction risk in bats. Using phylogenetic logistic regressions, we show that geographic range and island endemism are the strongest correlates of binary extinction risk. We also show that simulations using two models that trade-off between data complexity and data coverage provide similar estimates of extinction risk for species that have received a Red List assessment. We then use our model parameters to provide quantitative predictions of extinction risk for 60 species that have not received risk assessments by the IUCN. Our model suggests that at least 20 bat species should be treated as threatened by extinction. In combination with expert knowledge, our results can be used as a quick, first-pass prioritization for conservation action.

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Section: Phylogenetic Tree Constructionmentioning

confidence: 99%

Predicting Extinction Risk for Data Deficient Bats

Welch

Beaulieu

2018

Diversity

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“…Annotated gene sequences for CASP1, RIG-I, IRF3,NLRP3,ASC,TBK1,STING and TNF were downloaded from GenBank (Benson et al, 2015) for a range of mammalian species. These data represented 12 mammalian orders, with species from all four eutherian superorders, spanning more than 100 million years of mammalian evolution (derived from Meredith et al, 2011; laurasiatherian topology based on Foley et al, 2016; Myotis toplogy based on Ruedi et al, 2013) (Fig. S1).…”

Section: Positive Selection Testsmentioning

confidence: 99%

“…As CODEML requires a user input tree, a mammalian species tree based on Meredith et al (2011 and Ruedi et al (2013) was generated for each alignment. CODEML is designed to calculate likelihood-derived dN/dS rates (ω), where dN is defined as a number of non-synonymous substitutions per nonsynonymous sites and dS is a number of synonymous substitutions per synonymous sites.…”

Section: Positive Selection Testsmentioning

confidence: 99%

A Potent Anti-Inflammatory Response in Bat Macrophages May Be Linked to Extended Longevity and Viral Tolerance

Kacprzyk

Hughes

Pålsson-McDermott

et al. 2017

Acta Chiropterologica

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Bats are unique among mammals given their ability to fly, apparent tolerance of deadly viruses and extraordinary longevity. We propose that these traits are linked and driven by adaptations of the innate immune system. To explore this hypothesis we challenged macrophages from the greater mouse-eared bat, Myotis myotis and the house mouse, Mus musculus with Toll Like Receptors (TLRs) ligands, lipopolysaccharides, LPS and polyinosinic-polycytidylic acid, Poly(I:C). Macrophages from both species presented a high level of mRNA induction of inferon β (INF-β), tumor necrosis factor (TNF) and interleukin-1β (Il-1β). However, in bat macrophages, this antiviral, proinflammatory response was balanced by a sustained high-level transcription of the anti-inflammatory cytokine Il-10, which was not observed in mouse, potentially resulting from adaptive regulation in bats.Additionally, phylogenomic selection tests across the basal divergences in mammals (n = 39) uncovered bat-specific adaptations in six genes involved in antiviral and proinflammatory signalling. Based on this pilot study, we put forward a hypothesis that bats may have evolved unique anti-inflammatory responses to neutralize proinflammatory stimuli resulting from flight. This in turn may drive their extraordinary longevity and viral tolerance by limiting inflammation driven ageing and infection-induced immunopathology. Further data from other individuals and bat species are required to advance this intriguing hypothesis.

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“…The deep divergences within Myotis, amongst the Old World Clades, were poorly supported in both ML and BI analyses, and the exact relationships between the Eurasian clades differed between methods. These poorly supported deep nodes were previously reported by Ruedi et al (2013), and are unlikely to be resolved with a purely mitochondrial dataset such as this.…”

mentioning

confidence: 40%

The complete mitochondrial genome of the Bechstein’s bat, Myotis bechsteinii (Chiroptera, Vespertilionidae)

Jebb

Foley

Kerth³

et al. 2017

Mitochondrial DNA Part B

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In this study, we present the complete mitochondrial genome of the Bechstein’s bat, Myotis bechsteinii . The mitogenome is 17,151 bp in length and is AT-rich with base composition A (27.8%), C (22%), G (16.1%), and T (34.1%). The mitogenome shows conserved gene content and order similar with other mammalian mitogenomes, being composed of 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes, and one control region. The majority of genes are encoded on the H-Strand except for ND6 and 8 tRNAs as found in other bat species. The field identification of Myotis bechsteinii was confirmed by phylogenetic analyses using datasets comprising whole mitogenomes and COXI . This mitogenome is a resource for future studies of Myotis bats and other mammals.

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Molecular phylogenetic reconstructions identify East Asia as the cradle for the evolution of the cosmopolitan genus Myotis (Mammalia, Chiroptera)

Cited by 143 publications

References 61 publications

Predicting Extinction Risk for Data Deficient Bats

Predicting Extinction Risk for Data Deficient Bats

A Potent Anti-Inflammatory Response in Bat Macrophages May Be Linked to Extended Longevity and Viral Tolerance

The complete mitochondrial genome of the Bechstein’s bat, Myotis bechsteinii (Chiroptera, Vespertilionidae)

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