Molecular size and immunoreactivity of ethanol extracted soybean protein concentrate in comparison with other products

Zheng, Hongliang; Yan, Guosen; Marquez, Susan; Andler, Stephenia; Dersjant-Li, Y.; Mejı́a, Elvira González de

doi:10.1016/j.procbio.2020.06.007

Cited by 8 publications

(5 citation statements)

References 35 publications

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“…The latter negatively affect the production of nitric oxide [ 88 ], leading to delayed wound healing [ 89 ]. Moreover, soy protein isolates have been shown to contain two major allergens, glycinin and β-conglycinin [ 38 , 90 ]. However, to the best of our knowledge no study has focused on these side effects associated with the development of soy protein-based wound dressings.…”

Section: Electrospinning Of Plant-derived Proteins For Wound Healimentioning

confidence: 99%

“…To begin with, the diversity in extraction and purification methods has been shown to affect purity, composition and activity of the proteins. This in turn may influence the reproducibility during electrospinning, which is highly dependent on the homogeneity and surface charge of the material [ 5 , 36 , 37 , 38 , 57 ]. Unfortunately, there are currently no regulations in place to ensure homogeneity of structure and purity of protein-based materials [ 5 ].…”

Section: Opportunities and Challenges Of Using Proteins For Electrmentioning

confidence: 99%

“…Their stability, activity and degradation depend on the protein size, chemical structure, isolation and purification processes [5,35]. Different methods for protein extraction and purification may affect the obtained raw material's purity and composition [5,36,37], which in turn impacts reproducibility of the electrospinning process and properties of the final product [38]. Some of the main differences between plant-and animal-based proteins are their availability and price.…”

Section: Proteins As a Promising Starting Materials For Electrospun Wound Dressingsmentioning

confidence: 99%

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Electrospinning Proteins for Wound Healing Purposes: Opportunities and Challenges

Akhmetova

Heinz

2020

Pharmaceutics

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With the growth of the aging population worldwide, chronic wounds represent an increasing burden to healthcare systems. Wound healing is complex and not only affected by the patient’s physiological conditions, but also by bacterial infections and inflammation, which delay wound closure and re-epithelialization. In recent years, there has been a growing interest for electrospun polymeric wound dressings with fiber diameters in the nano- and micrometer range. Such wound dressings display a number of properties, which support and accelerate wound healing. For instance, they provide physical and mechanical protection, exhibit a high surface area, allow gas exchange, are cytocompatible and biodegradable, resemble the structure of the native extracellular matrix, and deliver antibacterial agents locally into the wound. This review paper gives an overview on cytocompatible and biodegradable fibrous wound dressings obtained by electrospinning proteins and peptides of animal and plant origin in recent years. Focus is placed on the requirements for the fabrication of such drug delivery systems by electrospinning as well as their wound healing properties and therapeutic potential. Moreover, the incorporation of antimicrobial agents into the fibers or their attachment onto the fiber surface as well as their antimicrobial activity are discussed.

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Section: Electrospinning Of Plant-derived Proteins For Wound Healimentioning

confidence: 99%

Section: Opportunities and Challenges Of Using Proteins For Electrmentioning

confidence: 99%

Section: Proteins As a Promising Starting Materials For Electrospun Wound Dressingsmentioning

confidence: 99%

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Electrospinning Proteins for Wound Healing Purposes: Opportunities and Challenges

Akhmetova

Heinz

2020

Pharmaceutics

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“…This may be due to the presence of residual isoflavones, which have demonstrated antioxidant, anti-inflammatory, and cytostatic properties, but are also known to have an adverse effect on nitric oxide production, resulting in delayed wound healing [ 67 ]. Moreover, SP isolates contain two major allergens, glycinin and conglycinin, which might counteract the healing process [ 68 ]. Despite these facts, several researchers have focused on the use of soy-based nanofibers for wound dressing and drug release purposes testing both in vitro and in vivo models.…”

Section: Recent Trends In Biomedical Application Of Electrospun Plant...mentioning

confidence: 99%

“…Successful electrospinning with water or mild buffers was proven so far only for canola and soy proteins. Using food-grade or generally recognized-as-safe solvents for electrospun biomedical materials is of the utmost requirement since harsh organic solvents bring risks of toxicity and environmental hazards [ 68 ]. However, water is not a perfect protein solvent because many proteins are quite hydrophobic and tend to aggregate or poorly unfold.…”

Section: Conclusion Prospects and Challengesmentioning

confidence: 99%

Agro-Industrial Plant Proteins in Electrospun Materials for Biomedical Application

et al. 2023

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Plant proteins are receiving a lot of attention due to their abundance in nature, customizable properties, biodegradability, biocompatibility, and bioactivity. As a result of global sustainability concerns, the availability of novel plant protein sources is rapidly growing, while the extensively studied ones are derived from byproducts of major agro-industrial crops. Owing to their beneficial properties, a significant effort is being made to investigate plant proteins’ application in biomedicine, such as making fibrous materials for wound healing, controlled drug release, and tissue regeneration. Electrospinning technology is a versatile platform for creating nanofibrous materials fabricated from biopolymers that can be modified and functionalized for various purposes. This review focuses on recent advancements and promising directions for further research of an electrospun plant protein-based system. The article highlights examples of zein, soy, and wheat proteins to illustrate their electrospinning feasibility and biomedical potential. Similar assessments with proteins from less-represented plant sources, such as canola, pea, taro, and amaranth, are also described.

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Integrated processing of soybean in a circular bioeconomy

Karp

Vandenberghe

Pagnoncelli

et al. 2022

Biomass, Biofuels, Biochemicals

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Molecular size and immunoreactivity of ethanol extracted soybean protein concentrate in comparison with other products

Cited by 8 publications

References 35 publications

Electrospinning Proteins for Wound Healing Purposes: Opportunities and Challenges

Electrospinning Proteins for Wound Healing Purposes: Opportunities and Challenges

Agro-Industrial Plant Proteins in Electrospun Materials for Biomedical Application

Integrated processing of soybean in a circular bioeconomy

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