Molecular toxicity of triclosan and carbamazepine to green algae Chlorococcum sp.: A single cell view using synchrotron-based Fourier transform infrared spectromicroscopy

4-Nonylphenol effects on rat testis and sertoli cells determined by spectrochemical techniques coupled with chemometric analysis

“…These findings, which suggest protein conformational changes in testicular cells and SCs after exposed to NP, are also consistent with those of other studies showing that NP is able to induce apoptosis in testicular cells in vivo and in SCs in vitro (Wu et al, 2009;Duan et al, 2016a;Duan et al, 2016b;Huang et al, 2016). The modifications of Amide I and II could predict the occurrence of protein aggregation from protein oxidation (Xin et al, 2017).…”

Denitrification-Potential Evaluation and Nitrate-Removal-Pathway Analysis of Aerobic Denitrifier Strain Marinobacter hydrocarbonoclasticus RAD-2

“…Therefore, strain RAD-2 could adapt to a lower temperature of 25 • C, which might increase its application in marine aquaculture, as temperatures 25-35 • C are the optimal environmental conditions for most cultured species. However, to better use the strain in practice, toxicology research should also be performed for strain RAD-2 in the future [38,39].…”

Towards identifying the mode of action of drugs using live-cell FTIR spectroscopy

“…[23][24][25][26] Infrared synchrotrons with brightness of several orders of magnitude higher than an ordinary Globar source have been used to partially overcome this problem. Using synchrotron sources, the measurement of infrared spectra of living cells within a reasonable time frame has been successfully demonstrated, 27,28 including the characterisation of normal cells from carcinoma, 29 response of cells to mechanical stress, 30 apoptotic pathways, 31 chemical stress, 12 optical stimulation, 32 protein aggregation, 17,33 drug actions, 10 toxicity in living algae 34 and imaging with subcellular spatial resolution using ZnS hemispheres. 35 However, access to synchrotron facilities are limited and therefore measurements of living cells that can be carried out in an ordinary laboratory remains highly desirable.…”