Molecular types and antimicrobial resistance profile of Staphylococcus aureus isolated from dairy cows and farm environments

Abstract

Sample collection and identificationA total of 180 lactating animals (166 cows and 14 buffalo) were sampled from seven farms. Before collection of clinical samples, a brief history of various animal

Bovine subclinical mastitis-associated methicillin-resistant Staphylococcus aureus, selective genotyping and antimicrobial susceptibility profile of the isolates in Kurdistan province of Iran

“…The selection pressure provoked by the abuse/misuse of beta-lactams is one of the main reasons for this phenomenon, as cloxacillin is frequently prescribed in treatment regime of intramammary infections (IMI) in the region without antibiogram test. Despite our results, some studies have represented high rates of resistance to tetracycline and cephalosporins among MRSA ( 21 , 22 , 33 , 34 ). High sensitivity to rifampin, lincosamides, macrolides, and aminoglycosides are in agreement with the results obtained elsewhere ( 10 , 32 , 34 , 35 ).…”

“…Despite our results, some studies have represented high rates of resistance to tetracycline and cephalosporins among MRSA ( 21 , 22 , 33 , 34 ). High sensitivity to rifampin, lincosamides, macrolides, and aminoglycosides are in agreement with the results obtained elsewhere ( 10 , 32 , 34 , 35 ). Besides, three (27.27%) of the MRSA isolates were multi-drug resistant (MDR).…”

“…The results revealed limited or no resistance to various antibiotic classes. The increasing frequency of resistance to beta-lactams in staphylococci has also been reported in some internal ( 10 , 33 ), and external studies ( 21 , 34 , 35 ). The selection pressure provoked by the abuse/misuse of beta-lactams is one of the main reasons for this phenomenon, as cloxacillin is frequently prescribed in treatment regime of intramammary infections (IMI) in the region without antibiogram test.…”

“…Besides, three (27.27%) of the MRSA isolates were multi-drug resistant (MDR). In addition, the fact concerning the horizontal transfer of most antibiotic-resistance genes in S. aureus isolated from mastitis udder has previously been reported ( 34 ). Fortunately, no resistance was observed against the exclusively prescribed medical antibiotics (fusidic acid, mupirocin, tobramycin, and vancomycin).…”

Prevalence, toxigenic potential and antimicrobial susceptibility profile of Staphylococcus isolated from ready-to-eat meats

“…This makes the global spread of antimicrobial-resistant or toxigenic organisms inevitable since the organisms do not respect international boundaries. Antibiotic-resistant Staphylococcus strains may cause diseases of high morbidity and mortality, lead to treatment failure and increase the cost of medical treatment and time of bedridden [ 36 ]. Exhibition of multidrug resistance to medical and veterinary essential antimicrobial agents, including cefoxitin, oxacillin and erythromycin as recorded in this study, is very worrisome because these drugs are still being heavily relied on, for the treatment of microbial diseases, especially in developing countries.…”