Molecularly Imprinted-Matrix Solid-Phase Dispersion for Selective Extraction of Five Fluoroquinolones in Eggs and Tissue

Yan, Hongyuan; Qiao, Fang; Row, Kyung Ho

doi:10.1021/ac070644q

Cited by 153 publications

(67 citation statements)

References 58 publications

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“…CRT has a quaternary amine cation function that may establish ionic interactions with carboxylate group (negatively charged) and also carboxylic and hydroxyl functions that are hydrogen acceptor/donors. Overall, these non-covalent interactions may be reversed, typically by wash in aqueous solution of an acid, a base, or methanol [48].…”

Section: Crt Selective Materialsmentioning

confidence: 99%

New molecularly-imprinted polymer for carnitine and its application as ionophore in potentiometric selective membranes

Moret¹,

Moreira²,

Almeida³

et al. 2014

Materials Science and Engineering: C

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a b s t r a c tKeywords: Carnitine Molecularly-imprinted polymer Sensor Potentiometry Urine Carnitine (CRT) is a biological metabolite found in urine that contributes in assessingseveral disease conditions, including cancer. Novel quick screening procedures for CRT are therefore fundamental. This work proposes a novel potentiometric device where molecularly imprinted polymers (MIPs) were used as ionophores. The host-tailored sites were imprinted on a polymeric network assembled by radical polymerization of methacrylic acid (MAA) and trimethylpropane trimethacrylate (TRIM). Non-imprinted polymers (NIPs) were produced as control by removing the template from the reaction media. The selective membrane was prepared by dispersing MIP or NIP particles in plasticizer and poly(vinyl chloride), PVC, and casting this mixture over a solid contact support made of graphite. The composition of the selective membrane was investigated with regard to kind/amount of sensory material (MIP or NIP), and the need for a lipophilic additive. Overall, MIP sensors with additive exhibited the best performance, with near-Nernstian response down to~1 × 10, at pH 5, and a detection limitof~8 × 10−5 mol L −1 . Suitable selectivity was found for all membranes, assessed by the matched potential method against some of the most common species in urine (urea, sodium, creatinine, sulfate, fructose and hemoglobin). CRT selective membranes including MIP materials were applied successfully to the potentiometric determination of CRT in urine samples.

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Section: Crt Selective Materialsmentioning

confidence: 99%

New molecularly-imprinted polymer for carnitine and its application as ionophore in potentiometric selective membranes

Moret¹,

Moreira²,

Almeida³

et al. 2014

Materials Science and Engineering: C

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“…Yan et al [124] foram os primeiros a propor o uso do MIP na extração por dispersão da fase sólida e empregaram esta técnica no preparo de amostras para análise de fluoroquinolonas em ovo, [124] carne [120,124] e em soro [123,125] por HPLC. As amostras foram preparadas pela homogeneização de quantidades iguais de amostra e do polí-mero, utilizando gral e pistilo.…”

Section: Extração Por Dispersão Em Fase Sólida Molecularmente Impressunclassified

Emprego de polímeros de impressão molecular em preparo de amostras para análise de compostos orgânicos: aplicações e tendências

Santos¹,

Abrão²,

Freitas³

et al. 2012

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ResumoOs polímeros de impressão molecular são materiais sintéticos dotados de sítios específicos de reconhecimento. Esses materiais são obtidos por reações de polimerização que fixam, estrategicamente, monômeros funcionais ao redor de uma molécula modelo de acordo com os grupos ligantes e com a estereoquímica de ambas as moléculas. Os MIPs têm sido amplamente empregados em procedimentos de preparo de amostras, como extração e microextração em fase sólida, extração sortiva em barra de agitação, extração com adsorvente magnético, microextração com sorvente empacotado, entre outras. Este artigo de revisão tem como objetivo apresentar o que há de mais recente no emprego de MIP para extração de compostos orgânicos, evidenciando as vantagens de cada aplicação, bem como as mais promissoras tendências que sustentam a evolução e o aperfeiçoamento de cada técnica. Palavras-chavePolímeros de impressão molecular; MIP; preparo de amostras.Molecularly imprinted polymers in sample preparation for organic compounds analysis: applications and trends AbstractMolecularly imprinted polymers are synthetic materials with molecular recognition ability. These materials are obtained by polymerization reactions that fix the functional monomers around the template molecule according with the binding groups and the stereochemistry of both molecules. The MIPs have been extensively used in several applications with emphasis for sample preparation procedures as solid phase extraction, solid phase microextraction, extraction by magnetic sorbents, microextraction by packed sorbent among others. So, the objective of this review is to present the novelty in MIP use for organic compounds extraction and point out the advantages of each application, as well as what is most promising in the evolution and improvement of each technique.

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“…Among them, the chromatographic method utilizing solid-phase extraction (SPE) as a pre-concentration step is widely adopted [2,15]. However, the drawbacks of being laborious, time-consuming and solvent intensive limited their application.…”

Section: Introductionmentioning

confidence: 99%

Upconversion fluorescence resonance energy transfer—a novel approach for sensitive detection of fluoroquinolones in water samples

Zhang

et al. 2016

Microchemical Journal

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A novel homogeneous assay method was put forth for simultaneous sensing of fluoroquinolone derivatives (FQs) in water utilizing the upconversion fluorescence resonance energy transfer (FRET) process based on the competitive reaction between dissolved FQs and labeled AuNPs for FQs Mab connected UCPs. The prepared size-tunable β-NaLuF4:Yb,Er,Gd upconversion phosphors (UCPs) were functionalized with carboxylic acid (COOH-) and monoclonal antibody (Mab, C2F3C2) to act as a donor. The gold nanoparticles (AuNPs) labeled with the corresponding antigen (ciprofloxacin-BSA) take the role of an acceptor. Under optimized conditions, the limit of detections (LODs) for three common FQs, enrofloxacin (ENR), ciprofloxaxin (CIP), and norfloxacin (NOR), were 0.19-0.32 ng/mL based on 3σ. The recoveries were found to be in the range of 73.5-114.5% (normalized value according to the cross-reactivity of Mab) for water samples (tap water, pond water and river water). The proposed approach possesses significant advantages as follows: (i) simple procedure (only one step) without washing and separation steps, and no sample pretreatment other than filtration; (ii) fast liquid-phase kinetics with shortened incubation time; and (iii) high tolerance to various interfering substances. All of which indicated its potentiality as an efficient biosensor towards the monitoring of FQs in aquatic environments.

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Molecularly Imprinted-Matrix Solid-Phase Dispersion for Selective Extraction of Five Fluoroquinolones in Eggs and Tissue

Cited by 153 publications

References 58 publications

New molecularly-imprinted polymer for carnitine and its application as ionophore in potentiometric selective membranes

New molecularly-imprinted polymer for carnitine and its application as ionophore in potentiometric selective membranes

Emprego de polímeros de impressão molecular em preparo de amostras para análise de compostos orgânicos: aplicações e tendências

Upconversion fluorescence resonance energy transfer—a novel approach for sensitive detection of fluoroquinolones in water samples

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