Molecularly imprinted polyaniline-ferrocene-sulfonic acid-Carbon dots modified pencil graphite electrodes for chiral selective sensing of D-Ascorbic acid and L-Ascorbic acid: A clinical biomarker for preeclampsia

Pandey, Indu; Jha, Shashank

doi:10.1016/j.electacta.2015.10.005

Cited by 58 publications

(35 citation statements)

References 34 publications

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“…The electrode presented good preparation reproducibility (RSD 3.3%), regeneration ability, and stability (one month) [ 111 ]. A MI-polyaniline ferrocene-sulfonic acid-carbon dots PGE could be used for over 40 days (when stored at room temperature) for chiral sensitive (LD at 10 −12 M level), accurate (RSD 3.4%), and selective recognition of L- and D-ascorbic acid from biological fluids in the presence of structurally close chiral or nonchiral molecules [ 115 ]. It is worth mentioning that the modified electrode surface was easy regenerated either by analyte elution using an adequate electrolyte [ 60 ] or by electrochemical dedoping [ 115 ].…”

Section: Discussionmentioning

confidence: 99%

Pencil Graphite Electrodes: A Versatile Tool in Electroanalysis

David

Popa

Buleandră

2017

Journal of Analytical Methods in Chemistry

203

106

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Due to their electrochemical and economical characteristics, pencil graphite electrodes (PGEs) gained in recent years a large applicability to the analysis of various types of inorganic and organic compounds from very different matrices. The electrode material of this type of working electrodes is constituted by the well-known and easy commercially available graphite pencil leads. Thus, PGEs are cheap and user-friendly and can be employed as disposable electrodes avoiding the time-consuming step of solid electrodes surface cleaning between measurements. When compared to other working electrodes PGEs present lower background currents, higher sensitivity, good reproducibility, and an adjustable electroactive surface area, permitting the analysis of low concentrations and small sample volumes without any deposition/preconcentration step. Therefore, this paper presents a detailed overview of the PGEs characteristics, designs and applications of bare, and electrochemically pretreated and chemically modified PGEs along with the corresponding performance characteristics like linear range and detection limit. Techniques used for bare or modified PGEs surface characterization are also reviewed.

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Section: Discussionmentioning

confidence: 99%

Pencil Graphite Electrodes: A Versatile Tool in Electroanalysis

David

Popa

Buleandră

2017

Journal of Analytical Methods in Chemistry

203

106

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“…Electrical contact with the instrument is realized by means of a conductive wire which was soldered or wrapped to the metallic part of the mechanical pencil holder [9,19,21,22,[24][25][26][27][28][29][30][31][32][33][34][35][36][37] (Figure 1a). A micropipette tip [38], an insuline syringe [39], a glass cappilary [40,41], or a plastic [16,[42][43][44][45][46] (Figure 1b) or Teflon tube [47][48][49][50][51][52] (Figure 1c,d) can also act as holder. An araldite mixture (epoxy resin, 1:1) [16,41,[43][44][45], bentonite [38,39], or cyanoacrylate glue [40] was used to fix the graphite lead into the support.…”

Section: Pge Manufacturing Proceduresmentioning

confidence: 99%

Recent Developments in Voltammetric Analysis of Pharmaceuticals Using Disposable Pencil Graphite Electrodes

et al. 2022

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The even growing production of both well-known and new derivatives with pharmaceutical action involves the need for developing facile and reliable methods for the analysis of these compounds. Among the widely used instrumental techniques, the electrochemical ones are probably the simplest and the most rapid, also having good performance characteristics. However, the key tool in electroanalysis is the working electrode. Due to the inherent electrochemical and economic advantages of the pencil graphite electrode (PGE), the interest in its applicability in the analysis of different analytes has continuously increased in recent years. Thus, this paper aims to review the scientific reports published in the last 10 years on the use of the disposable eco- and user-friendly PGEs in the electroanalysis of compounds of pharmaceutical importance in different matrices. The PGE characteristics and designs (bare or modified with various types of materials), along with their applications and performance parameters (e.g., linear range, limit of detection, and reproducibility), will be discussed, and their advantages and limitations will be critically emphasized.

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“…Although lots of spectroscopic analytical methods based on new nanomaterials have been proposed for chiral recognition, expensive optical instruments and limited detection sensitivity still restrict the application of chiral analysis. Due to the advantages of low‐cost and miniaturized device, simple detection process, and high‐sensitive and real‐time readout, 9 the electrochemical analytical method as a promising candidate attracts the extensive attention for enantioselective discrimination. Prasad et al 8 subtly combined gold nanoparticle and multiwalled carbon nanotube to construct a composite‐based dual imprinted electrochemical sensor for ultratrace analysis of D/L‐Asp.…”

Section: Introductionmentioning

confidence: 99%

Bovine serum albumin‐coated titanium dioxide modified electrochemical interface for enantioselective discrimination of D/L‐aspartic acid

Wei

Chen

et al. 2021

Chirality

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Due to the similar physicochemical properties, the discrimination of chiral isomers faces huge challenges in drug production and biochemical analysis.Herein, the bovine serum albumin-coated titanium dioxide (bovine serum albumin [BSA]/TiO 2 ) was modified as a novel electrochemical interface for efficient, simple, and enantioselective discrimination of aspartic acid enantiomers (D/L-Asp) based on the electrochemical impedance spectroscopy (EIS). Utilizing the structural characteristics of large cavity and high specific surface area, TiO 2 material provided sufficient space for adequate loading of BSA. The BSA/TiO 2 electrochemical interface was successfully fabricated to support abundant chiral recognition sites. The enantioselective discrimination of D/L-Asp was achieved on the interface with a good linear relationship against the impedance difference in the concentration range from 1 to 1000 nM with the detection limit of 0.37 nM for L-Asp and 0.94 nM for D-Asp, reaching the identification coefficient (I c = K L /K D ) of 1.85. The proposed interface is easy to form with a stable formation of BSA in TiO 2 microporous architecture, which maintained the desired stability and reproducibility. For the unknown racemic solution, I c levels of different enantio-ratios of D/L-Asp were effectively obtained to evaluate the chiral percentage of racemic sample. The possible mechanism of chiral recognition by density function theory (DFT) was confirmed with a stronger adsorption to L-Asp in accordance with our experiment results, reinforcing the validity of our presented interface. The BSA/TiO 2 electrochemical interface with robust enantioselective discrimination of D/L-Asp has great potential for the practical application in pharmaceutical surveillance and food security.

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Molecularly imprinted polyaniline-ferrocene-sulfonic acid-Carbon dots modified pencil graphite electrodes for chiral selective sensing of D-Ascorbic acid and L-Ascorbic acid: A clinical biomarker for preeclampsia

Cited by 58 publications

References 34 publications

Pencil Graphite Electrodes: A Versatile Tool in Electroanalysis

Pencil Graphite Electrodes: A Versatile Tool in Electroanalysis

Recent Developments in Voltammetric Analysis of Pharmaceuticals Using Disposable Pencil Graphite Electrodes

Bovine serum albumin‐coated titanium dioxide modified electrochemical interface for enantioselective discrimination of D/L‐aspartic acid

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