Molecularly Imprinted Solid-Phase Extraction in the Analysis of Agrochemicals

Yi, Ling-Xiao; Fang, Rou; Chen, Guanhua

doi:10.1093/chromsci/bmt024

Cited by 59 publications

(43 citation statements)

References 105 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was initially proposed by Sellergren et al in 1994 for extracting pentamidine present at low concentration in urine [27]. Since this first application, numerous MIPs were developed for the selective extraction of target analytes from complex samples [28][29][30][31]. Because of their high selectivity, they have been also already successfully used in several other fields such as sensors [32][33][34], bioassays [35,36] and enantiomeric separation [37].…”

Section: Introductionmentioning

confidence: 99%

Molecularly imprinted polymers for the determination of organophosphorus pesticides in complex samples

Boulanouar

Mezzache

Combès

et al. 2018

Talanta

124

View full text Add to dashboard Cite

Organophosphorus compounds constitute an important class of pesticides whose the toxicity of which arises from the inhibition of the acetylcholinesterase enzyme. They exhibit a wide range of physico-chemical properties, thus rendering their determination in complex oil samples particularly difficult. To facilitate their analysis at the trace level in various samples (environmental waters, soils, vegetables…), molecularly imprinted polymers (MIPs) that are synthetic polymers possessing specific cavities designed for a target molecule have been prepared. Often called synthetic antibodies, MIPs can replace antibodies in different application fields. Indeed, as immunosorbents, MIPs can be used as selective sorbents for the solid phase extraction of target analytes from complex matrices or as recognition elements in sensors. Their synthesis, characterization and use as selective sorbent for the selective recognition of organophosphorus pesticides have been already largely described and are summarized in this review.

show abstract

Section: Introductionmentioning

confidence: 99%

Molecularly imprinted polymers for the determination of organophosphorus pesticides in complex samples

Boulanouar

Mezzache

Combès

et al. 2018

Talanta

124

View full text Add to dashboard Cite

show abstract

“…Removal of the template leaves cavities that are complementary to the original template molecule or its structural analogs in terms of shape, size, and functional group in the resulting polymer. Over the past decades, MIPs have been prepared using various kinds of compounds as templates that had been hard to separate by conventional ways, and they have played important roles in many fields, including solid phase extraction, enantiomer separation, and sensors and membranes . The application of the molecular imprinting technique (MIT) in sample pretreatment has attracted increasing attention because the selectivity of the pretreatment procedure can be improved and the analysis method can be simplified.…”

Section: Introductionmentioning

confidence: 99%

Comparative analysis of atrazine molecularly imprinted polymers using acetonitrile and toluene as solvents

Zhang

Kong

et al. 2018

J of Applied Polymer Sci

View full text Add to dashboard Cite

Acetonitrile and toluene are solvents commonly used for the synthesis of atrazine molecularly imprinted polymers (MIPs), but their effects have seldom been compared in the same imprinting system. In this paper, effects of the two solvents in an atrazine molecular imprinting system were evaluated theoretically and experimentally. A polarizable continuum model was adopted, and it was found that using the two solvents, the energy difference for the atrazine–methacrylic acid complex between vacuum and solution was not the same. The two types of MIPs prepared using different solvents vary in morphology, porosity, binding capacity, and specificity. All of these results suggest that the abilities of the solvents used to form hydrogen bonds with other compounds in the system are different. The porogen imprinting effect of the solvents also has an influence on binding capacity. Compared to MIPs synthesized using acetonitrile as solvent (MIPs‐ACN), MIPs synthesized using toluene as solvent (MIPs‐PhMe) have fewer but larger pores and exhibit much higher adsorption capability but less rigorous specificity. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47190.

show abstract

“…Different approaches have been proposed to produce specific affinity-based stationary phases, developing selective ligands such as molecularly imprinted polymers, aptamers, or peptides proposed as alternative candidates to antibodies which are expensive and challenging to prepare [7][8][9][10][11]. These synthetic molecular traps are able to selectively interact with analytes, similarly to biological receptors but offering some advantages such as low costs, rapid synthesis, and stability.…”

Section: Introductionmentioning

confidence: 99%

Solid-Phase Extraction of Pesticides by Using Bioinspired Peptide Receptors

Lanzone

Sergi

Mascini

et al. 2015

Journal of Chemistry

View full text Add to dashboard Cite

A virtual development of hexapeptide receptors bioinspired by the acetylcholinesterase enzyme active site is proposed. A semicombinatorial approach was applied to generate a virtual hexapeptides library with different affinity properties towards organophosphate and carbamate pesticides. The virtual screening process was addressed to obtain peptides able to separate pesticide subclasses in the experimental work. Three hexapeptides, two generated by molecular modeling and one having a scrambled sequence, were used as selective sorbent materials for pesticides in preanalytical solid-phase extraction (SPE) method. Selective adsorption and cross-reactivity were tested directly on a mix of four pesticides (carbaryl, chlorpyrifos-ethyl, malathion, and thiabendazole) having different structures and physico-chemical properties, at a total concentration of 120 ppb (each pesticide at concentration of 30 ppb). The results were compared to traditional sorbent material such as C-18 and strata-X. Data showed that only one of the hexapeptides virtually designed had significant differences in competitive absorption between aliphatic pesticide malathion, fungicide thiabendazole chosen as negative control, and aromatic pesticides. These results partially supported the simulated strategy.

show abstract

Molecularly Imprinted Solid-Phase Extraction in the Analysis of Agrochemicals

Cited by 59 publications

References 105 publications

Molecularly imprinted polymers for the determination of organophosphorus pesticides in complex samples

Molecularly imprinted polymers for the determination of organophosphorus pesticides in complex samples

Comparative analysis of atrazine molecularly imprinted polymers using acetonitrile and toluene as solvents

Solid-Phase Extraction of Pesticides by Using Bioinspired Peptide Receptors

Contact Info

Product

Resources

About