Momentary Fluctuations of Intraocular Pressure in Normal and Glaucomatous Eyes

Piltz, Jody R.; Starita, R L; Miron, M.S.; Henkind, Paul

doi:10.1016/0002-9394(85)90365-4

Cited by 22 publications

(9 citation statements)

References 13 publications

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“…45 After repeated measurements with the Goldmann, readings have been shown to reduce by an average of 3 mmHg.46 NCTs do not share this characteristic. 44 Although the number of subjects in our study is smaller than in other reported series, we believe the results suggest that NCT using a mean of four readings per eye should be con sidered as the first line screening test to iden tify those at risk of lOP related disease.…”

Section: Discussionmentioning

confidence: 51%

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Screening for glaucoma in the community by non-ophthalmologically trained staff using semi automated equipment

Vernon

Henry

Cater

et al. 1990

Eye

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SummaryEighty-nine and a half per cent of the population of a general practice over the age of 49 years were screened for glaucoma and high risk ocular hypertension requiring treatment. Screening took place using semi-automated intraocular pressure and visual field equipment operated by non-ophthalmologicaUy trained staff. An experi enced ophthalmologist examined aU patients in a single blind manner to reduce false negatives to a minimum. Patients suspected of requiring treatment on the grounds of raised intraocular pressure, abnormal visual fields or suspicious optic discs were subsequently examined in a hospital clinic. Treatment criteria, as commonly prac ticed, were carefully defined and the sensitivities and specificities of the methods of screening used were calculated. One and three tenths per cent of the practice popula tion were known to be receiving treatment prior to the study and a further 1.4%were found to require treatment after screening.The sensitivity and specificity of the non-contact tonometer were 91.7% and 95.6% respectively with a predictive power of 22.5% for a positive result. The mean time taken to perform the test in both eyes was two minutes. Seventy per cent of the patients with pressures over 22 mmHg in both eyes on screening were found to require treatment. The routine use of the field screener did not increase either the sensitivity or specificity of the screening process but its use in cases with raised intraocular pressure is advised to indicate the degree of urgency of the referral.An algorithm based on the results of the study is suggested when planning the use of semi-automated equipment to screen for ocular disease related to raised intra ocular pressure.Chronic Simple Glaucoma (CSG) is a com mon disease of middle age and the elderly, prevalence rising from 0.5-1 % of the popula tion over the age of 401,2 to 6.6% over 75.3 It is responsible for up to 16.8% of registrable blindness in the population of the United Kingdom aged over 65 years.4CSG is characterised by a triad of physical signs: raised intraocular pressure (lOP),

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Section: Discussionmentioning

confidence: 51%

“…It has been demon strated that the ocular pulse amplitude is greater in those with glaucoma. 44 As we used four readings per eye to produce our mean, random sampling with the PuIs air may pro duce a higher mean in those prone to lOP related damage than in normal subjects with lOP around 20 mmHg or in those with benign 'ocular hypertension'.…”

Section: Discussionmentioning

confidence: 99%

Screening for glaucoma in the community by non-ophthalmologically trained staff using semi automated equipment

Vernon

Henry

Cater

et al. 1990

Eye

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“…Part of this variation is due to a circadian variation in aqueous humor production (Brubaker, 1991). Apart from these physiological circadian variations in the IOP, short-term fluctuations seem to be present particularly in glaucoma (Piltz et al, 1985). Such short-term variations are unlikely to be due to rapid changes in aqueous flow and fluctuations in outflow probably contribute to the overall variations in IOP.…”

Section: Introductionmentioning

confidence: 99%

Acetylsalicylic Acid does not Reduce the Intraocular Pressure Variation in Ocular Hypertension or Glaucoma

Lindén

Alm

2000

Experimental Eye Research

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“…2 NCT with the American Optical instrument has been reported to produce readings which, when repeated a number of times in quick succession, have a range spanning only 2 or 3 mm Hg in normals. 3 The Keeler Pulsair NCT was introduced in the late 1980s, and uses a lower pulse volume and pressure than the American Optical instrument (personal communication, Keeler Ltd). The recently introduced Pulsair 2000 incorporates software to enable the operator to take sequential readings without moving the instrument away from the eye.…”

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confidence: 99%