Monckeberg's Arteriosclerosis

Cutaneous Erythema, With or Without Necrosis, Localized to the Legs and Feet—a Lesion in Elderly Diabetics

“…In discussing the incidence of arteriosclerosis a distinction should be made between calcification of the media (Monckeberg) and lesions of t h e intima (atherosclerosis). The former does not usually affect the arterial lumen (41) and is generally accepted as being more frequent among diabetics, but many authors (29,44,65) have regarded it as lacking in clinical significance. On the other hand it is controversial whether intimal lesions are more common among diabetics than among non-diabetics (8,25,57).…”

Monckeberg's sclerosis in temporal artery biopsy specimens

“…The infrequent occurrence of this condition in the temporal artery and the presence of a fragmented internal elastic lamina should not be erroneously interpreted as sequelae of previous arterial inflammation. The pathophysiology of Monckeberg’s arteriosclerosis is still unclear, but it can be induced in animal models by injecting adrenalin, nicotine, parathyroid hormone, and vitamin D 2. In addition, lumbar sympathectomy has been shown to promote occurrence of Monckeberg’s arteriosclerosis of the lower extremities in humans 3.…”

Calcification in Breast Arteries

“…As degeneration of elastic fibers in the skin and arteries is related to ageing (3), the finding of an age-related arterial calcification in the breast (p <O,OO I ) is not surprising, and it might be considered a normal age or involutionary change, as in the uterus (8). The distribution of the three grades of calcified vessels might imply a development from grade I to grade 111 ( I 3), which is very similar to and probably represent Monckeberg's medial sclerosis (20).…”