2017
DOI: 10.3389/fped.2017.00046
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Monitoring Cerebral Oxygenation in Neonates: An Update

Abstract: Cerebral oxygenation is not always reflected by systemic arterial oxygenation. Therefore, regional cerebral oxygen saturation (rScO2) monitoring with near-infrared spectroscopy (NIRS) is of added value in neonatal intensive care. rScO2 represents oxygen supply to the brain, while cerebral fractional tissue oxygen extraction, which is the ratio between rScO2 and systemic arterial oxygen saturation, reflects cerebral oxygen utilization. The balance between oxygen supply and utilization provides insight in neonat… Show more

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Cited by 80 publications
(81 citation statements)
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References 127 publications
(144 reference statements)
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“…No changes in rSO 2 were detected, despite a decrease in CBF and PtO 2 , and an increase in blood lactate during treatments. This is surprising, as NIRS monitoring has recently been recommended in identifying and preventing PCO 2 ‐induced cerebral hypo‐ and hyperperfusion . The present study might have been underpowered to detect alterations in rSO 2 , especially as NIRS measurements have a high inherent physiological variation.…”
Section: Discussionmentioning
confidence: 88%
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“…No changes in rSO 2 were detected, despite a decrease in CBF and PtO 2 , and an increase in blood lactate during treatments. This is surprising, as NIRS monitoring has recently been recommended in identifying and preventing PCO 2 ‐induced cerebral hypo‐ and hyperperfusion . The present study might have been underpowered to detect alterations in rSO 2 , especially as NIRS measurements have a high inherent physiological variation.…”
Section: Discussionmentioning
confidence: 88%
“…This is surprising, as NIRS monitoring has recently been recommended in identifying and preventing PCO 2 -induced cerebral hypo-and hyperperfusion. 18 The present study might have been underpowered to detect alterations in rSO 2 affected by contamination from extracranial tissues. 24 Therefore, the NIRS sensors in the present study were positioned on the basis of computer tomography images obtained from a previous experiment to be appropriate for brain tissue sampling.…”
Section: Discussionmentioning
confidence: 97%
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