“…Several antibiotic compounds (e.g., sulfamethoxazole, lincomycin, and erythromycin) have been detected in groundwater in Europe and North America, with maximum concentrations in the range of 5.7-103 ng L −1 (Barnes et al, 2008;Garcia-Galan et al, 2010). Moreover, a variety of industrial chemicals (e.g., detergents, fire retardants, and plasticizers), PPCPs (e.g., anti-inflammatories, β-blockers, drugs of abuse, antiseptics, preservatives, and sweeteners) and their metabolites have been observed in groundwater Grujic et al, 2009;Hohenblum et al, 2004;Houtz et al, 2013;Jurado et al, 2012a,b;Kahle et al, 2009;Kuroda et al, 2012;Lopez-Serna et al, 2013;Loos et al, 2010;Osenbruck et al, 2007;Schaider et al, 2014;Teijon et al, 2010;Vulliet and Cren-Olive, 2011;Wolf et al, 2012). The presence of some antibiotics has also been reported in groundwater in North China due to soil manure applications (Hu et al, 2010).…”