Monitoring Of Side Effects Of Anti-Tuberculosis Drugs (ATD) On The Intensive Phase Treatment Of Pulmonary TB Patients In Makassar

Abbas, Akhmadi

doi:10.19184/ams.v3i1.4093

Cited by 5 publications

(8 citation statements)

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“…Some patients report experiencing the effects of nausea, dizziness, muscle aches which according to them torture themselves and interfere with daily activities so that they decided to stop TB treatment. Previous study stated that the experience of side effects of anti-TB drugs such as joint pain, nausea, dizziness, vomiting (Abbas, 2017) which is uncomfortable for the patients causes the patient to stop treatment (Sang, Obwoge, Kangethe, Ayiro, & Changeiywo, 2017). Health professional workers need to approach TB patients to provide counseling to increase the motivation of TB patients in completing TB treatment and provide appropriate interventions to reduce discomfort due to the side effects of anti-TB drugs.…”

Section: Discussionmentioning

confidence: 99%

Barriers in Tuberculosis Treatment in Rural Areas (Tengger, Osing and Pandalungan) in Indonesia Based on Public Health Center Professional Workers Perspectives: a Qualitative Research

Sulistyono¹,

Susanto²,

Tristiana³

2019

J. Ners

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Introduction: Tuberculosis (TB) is still one of the main health problems in Indonesia. Various efforts have been made by the government to handle the TB problem in Indonesia, one of which is implementing a direct observed therapy short course (DOTS) program. However, the handling of TB disease in Indonesia, especially in rural areas is still not optimal. This study aims to explore barriers to the handling of TB in rural areas from the perspective of public health center professionals.Methods: This study is a qualitative research with a phenomenological approach. Sampling was done by purposive sampling with a sample of 8 participants. Data is collected through focus group discussions. Thematic analysis is carried out using colaizi step.Results: This study obtained two themes. Theme 1 is the barriers in the aspect of TB patients and Theme 2, which is barriers from the aspect of health care facilities.Conclusion: This study obtained two themes. Theme 1 is the barriers in the aspect of TB patients and Theme 2, which is barriers from the aspect of health care facilities.

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Section: Discussionmentioning

confidence: 99%

Barriers in Tuberculosis Treatment in Rural Areas (Tengger, Osing and Pandalungan) in Indonesia Based on Public Health Center Professional Workers Perspectives: a Qualitative Research

Sulistyono¹,

Susanto²,

Tristiana³

2019

J. Ners

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“…Efek samping yang terjadi memang tidak berbahaya bagi pasien tetapi cukup membuat pasien merasa khawatir. Penelitian yang menganalisis efek samping OAT dilakukan oleh Fitriani (2019) didapatkan 26 orang(60,5%) pasien TB paru yang berobat merasakan efek samping ringan seperti mual,sakit perut, urin berwarna kemerahan dan lain-lain, sedangkan sebanyak 17 orang (39,5%) mengalami efek samping berat seperti kemerahan pada kulit dan rasa terbakar pada kaki [13] dan penelitian Abbas (2017) efek samping obat yang paling umum adalah nyeri sendi, dan efek samping lain 81% adalah mual (79,3%), gatal-gatal (77,6%) dan kehilangan nafsu makan (75,9%), pusing (67,2%), kesemutan (50%), tuli (6,9%) [21]. Sehingga dapat disimpulkan berdasarkan penelitian-penelitian yang telah dilakukan, rata-rata pasien yang menjalani pengobatan OAT merasakan efek samping ringan hingga berat dan efek samping tersebut merupakan suatu kondisi yang tidak diinginkan meskipun obat sudah digunakan sesuai dengan dosis dan pemakaian dan mempengaruhi kepatuhan pasien dalam meminum obat.…”

Section: Pendahuluanunclassified

“…Keluhan lainnya yang sering dirasakan oleh pasien yaitu mual (79,3%), gatal (77,6%), selera makan menurun (75,9%), pusing (67,2%) serta kesemutan (50%). Efek yang jarang dialami yaitu gangguan pada pendengaran (6,9%) (Abbas, 2017). Sari, 2014 menemukan dalam penelitiannya gejala efek samping pada pasien TB Paru adalah warna merah pada urine, kesemutan, mual, pusing, gatal,nyeri sendi/pegal, ruam, penglihatan terganggu.…”

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“…Meski demikian, proporsi penderita yang mengalami efek samping OAT masih tinggi. Data menunjukkan bahwa hingga berakhirnya masapengobatan tahap intensif, proporsi penderita yang mengalami efek samping sebesar 67,2% (Abbas, 2017) Penelitian Amsari et al, (2019) Pengaruh Efek Samping OAT terhadap Kepatuhan Minum Obat Pada Pasien TBC berdasarkan hasil penelitian menunjukkan bahwa, efek samping OAT ringan yang patuh minum obat sebanyak 15 orang (37,5%), responden yang mempunyai efek samping OAT ringan yang tidak patuh minum obat sebanyak 0 orang (00,0%), responden yang mempunyai efek samping OAT berat dan patuh minum obat sebanyak 11 orang (65%), dan responden yang mempunyai efek samping berat dan tidak patuh minum obat sebanyak 14 orang (35%) di Puskesmas Pekauman Banjarmasin. Hasil analisis statistik antara pengaruh efek samping OAT terhadap kepatuhan minum obat pada pasien TB dengan menggunakan uji korelasi Spearman rank, diperoleh nilai ρ value = 0,000 < α 0,05 yang artinya Ha diterima, artinya ada hubungan yang signifikan antara pengaruh efek samping OAT terhadap kepatuhan minum obat pada pasien TB, dengan nilai Corelations coefision r = -0,568.…”

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Korelasi Efek Samping Obat Anti Tuberkulosis dengan Kepatuhan Pengobatan Pasien TB Paru

Ruben,

Tondok,

Suprayitno

2023

jharma

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Pulmonary TB is an infectious disease which is a major problem for health in communities, especially in developing countries. The incidence of TB in Indonesia in 2020 is 301 per 100,000 population, the death rate is 34 per 100,000 population. Pulmonary TB patients who do not comply with taking medication can cause a decrease in the cure rate and an increase in the death rate. OAT side effects are one of the causes of non-compliance. This study aims to determine the correlation of OAT side effects with adherence in pulmonary TB patients. The research design was an analytic observational cross sectional study approach and was carried out at the Asolokobal Health Center with a total sample of 30 respondents. Respondents filled out a questionnaire and gave a checklist on the perceived side effects of OAT, compliance was measured with the Guttman scale, the answers "Yes" or "No". The statistical test used is Chi Square with the alternative Fisher's Exact Test. The results of the study showed that 20 respondents (66.7%) adhered to the level of compliance with mild drug side effects. The level of compliance of respondents with symptoms of severe side effects who adhered to it was 6 respondents (20.0%), the level of compliance of respondents with symptoms of severe side effects who did not comply was 4 respondents (13.3%). Fisher's Exact Test, obtained p value = 0.008. It was concluded that there is a correlation between the side effects of anti-tuberculosis drugs and adherence to treatment of pulmonary TB patients.

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“…Even color vision is affected before visual field and visual acuity. 7 Isoniazid has been a key treatment drug since 1952. It has adverse reactions, are hepatotoxicity and neurotoxicity.…”

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confidence: 99%

Assessment of Optic Nerve Changes in Patients Receiving Anti-Tuberculosis Drugs at Different Time Interval

Abbas¹,

Sammad²,

Akhtar³

et al. 2022

J. Bahria Uni. Med. Dent. Coll.

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Objectives: To assess optic nerve changes in patients receiving anti-tuberculosis drugs and to assess optic nerve changes at different time intervals of therapy. Study design and settings: Descriptive cross-sectional study was conducted from August 2021 to November 2021 in Madinah Teaching Hospital, Faisalabad. Methodology: 200 eyes of 100 patients receiving anti-tuberculosis therapy since 2-month, 4-month, 6 month and 8 months were taken. Patients did not have any systemic disease other than Tuberculosis. Indirect Ophthalmoscopy was performed to assess changes in fundus and optic nerve head. Optical Coherence Tomography was performed for assessment of retinal nerve fiber layer thickness and cup to disc ratio. Data was analysed by using descriptive statistics and chi-square test with SPSS version 20. Results: In 2 months there was 16(66.66%) normal fundus, 8(33.33%) glaucomatous optic disc cupping. In 4 months, there was 12(15.38%) normal fundus, 16(20%) optic atrophy, 16(20%) optic neuropathy, 4.00(5%) optic neuritis and 30(38%) glaucomatous optic disc cupping. In 6 months, there was 7(21%) normal fundus, 4(12.5%) optic atrophy and 21(50%) optic neuropathy. In 8 months, there was 24(36%) optic atrophy, 34(51.5%) optic neuropathy, 4(6%) optic neuritis and 4(6%) Glaucomatous optic dis cupping (P 0.00). Result of this study also shows that retinal nerve fiber layer thickness is normal in 83(41.5%), increase in 4(2.0%) and decrease in 113(56.5%). Conclusions: This study concluded that anti-tuberculosis drugs responsible for optic nerve changes and severity of optic nerve changes increase when duration of therapy increases

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Monitoring Of Side Effects Of Anti-Tuberculosis Drugs (ATD) On The Intensive Phase Treatment Of Pulmonary TB Patients In Makassar

Abstract: AbstrakEfek samping Obat Anti Tuberkulosis (OAT) 81% joint pain, nausea 79.3%, 77.6% itching, loss of appetite 75.9%, 67.2% dizziness, tingling 50%, vomiting 41.4%, 34.5% abdominal pain, visual disturbances 27.6%, headache 24.1% and 6.9%

Cited by 5 publications

References 3 publications

Barriers in Tuberculosis Treatment in Rural Areas (Tengger, Osing and Pandalungan) in Indonesia Based on Public Health Center Professional Workers Perspectives: a Qualitative Research

Barriers in Tuberculosis Treatment in Rural Areas (Tengger, Osing and Pandalungan) in Indonesia Based on Public Health Center Professional Workers Perspectives: a Qualitative Research

Korelasi Efek Samping Obat Anti Tuberkulosis dengan Kepatuhan Pengobatan Pasien TB Paru

Assessment of Optic Nerve Changes in Patients Receiving Anti-Tuberculosis Drugs at Different Time Interval

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