Monkeypox: Treatment, Vaccination, and Prevention

Abstract

In regions where the disease is endemic, Monkeypox (MPV) transmission related to healthcare has been seen on numerous occasions. This disease has episodes of occurrence in certain regions around the globe, such as in the Democratic Republic of Congo's (DRC) Tshuapa region. Here, the disease was found with a prevalence of 0.35 per 1000, as per data collected by the Centers for Disease Control and Prevention (CDC) of the United States (US). Data also shows approximately 100 confirmed cases of MPV for every infection among Healthcare Workers (HCWs). These findings and scientific research on burns, superficial wounds, herpes, eczema vaccine, and other conditions indicate that MPV sufferers might get an advantage from medical care to lessen the effects of weakened skin and mucosa. This should involve guarding delicate anatomical areas like the eyes and genitalia, maintaining enough hydration and nourishment, and preventing and treating consequences like secondary bacterial diseases. In the DRC, this disease was first recognized in 1970. Since then, it has spread to numerous nations around the globe and gained substantial epidemiological significance. The most recent epidemic has taken place in 2022 worldwide. The viruses that cause MPV and cowpox are currently regarded as emerging. Because of the rise in international travel, the popularity of exotic pets, and the decline in smallpox vaccination rates, they pose a significant danger of spreading. Although it is believed that this viral illness will eventually go away on its own, the possibility of the pandemic raises several serious problems for the general public's health. In addition to providing a broad overview of the Monkeypox Virus (MPXV), this study will detail the epidemiology, clinical hallmarks, assessment, and treatment of MPV sufferers.

Monkeypox virus (MPXV): A Brief account of global spread, epidemiology, virology, clinical features, pathogenesis, and therapeutic interventions

“…Even though their specificity is poor, rapid antigen and antibody tests are nonetheless often employed. The collection, storage, transportation, processing, interpretation, and reporting of laboratory results all require better infrastructure [ 57 ].…”

Knowledge, concerns, and vaccine acceptance related to Mpox (Monkeypox) among university students in North and Northeast China: An online cross-sectional study

“… 4–6 The increase in international travel, the popularity of new pets, and the decline in smallpox vaccination protection all contribute to increase the risk of Mpox transmission. 7 , 8 Mpox virus could spread by animal-to-human transmission or human-to-human transmission. 6 , 9 The routes of Mpox human-to-human transmission included intimate or sexual contact, contaminated surfaces or skin-to-skin contact, and respiratory droplets contact.…”

Comparación estadística de la infección por la viruela del mono (MPOX) entre Norteamérica y Sudamérica

“…Sin embargo, se han realizado algunos estudios en animales y humanos que sugieren que la vacuna contra la viruela puede ofrecer una protección parcial contra el HPX. Además, en cualquier caso, la prevención de la infección por HMPX se basa en la adopción de medidas preventivas, como el lavado frecuente de manos y el uso de equipo de protección personal, especialmente para aquellos que trabajan en contacto con animales infectados o pacientes (Lum et al, 2022;Ahmed et al, 2022;Shah & Fulmali, 2023).…”