“…MPXV infection is diagnosed using clinical signs and laboratory tests. The symptoms of MPXV are similar to those of smallpox but less severe [ 25 ]. The incubation period for MPX is typically 7–14 days, but it can last up to three weeks [ 26 ].…”
“…MPXV infection is diagnosed using clinical signs and laboratory tests. The symptoms of MPXV are similar to those of smallpox but less severe [ 25 ]. The incubation period for MPX is typically 7–14 days, but it can last up to three weeks [ 26 ].…”
“…Some of the cases reported in May 2022 also involved genitourinary skin lesions. 16 Figure 2 A visual example of Monkeypox rash. The rash is in form of lesions that are the commonest sign of Monkeypox disease.…”
Section: Clinical Features Of Human Monkeypox Virus Infectionmentioning
Recently, the World Health Organization (WHO) declared the human monkeypox virus disease an international health emergency. In the past decades, infectious disease epidemics have significantly impacted low- and middle-income countries (LMICs), with coronavirus disease-2019 (COVID-19) being the most recent. LMICs, particularly in Africa and Asia, responded reasonably well by strengthening health systems, including infection prevention and control strategies, laboratory systems, risk communication, and training of essential healthcare workers for surge capacity in preparation for and response to COVID-19. With the possibility of other epidemics, such as the current epidemic of human Monkeypox, a consolidated global response is required. This article discusses lessons learned from previous Ebola and COVID-19 outbreaks and also provides recommendations on how these lessons can be useful to strengthen monkeypox disease outbreak preparedness and response in LMIC.
“…The rate of case fatalities in the African clade was 10.6% vs 3.6% for the West African clade [9]. The World Health Organization changed the designations of the clades to I and II, respectively, due to the current virus outbreak's spread outside of Africa and advised against stigmatic because homosexual males (MSM) are more frequently death as a result of it [10,11].…”
The non-endemic monkeypox outbreak in 2022 is the largest outside of Africa in recorded history. The assumption is that monkeypox, an emerging zoonotic disease, has a high potential for epidemic spread with increased human outbreaks in recent years. The vaccinia-based smallpox vaccination has been discontinued globally for more than 40 years. Additionally, there are now more vulnerable populations. Populations who have not received the vaccine are more susceptible to monkeypox viral infection, while smallpox cannot spontaneously recur. As a member of the orthopoxvirus family and because of its potential for rapid adaptation in humans, the monkeypox virus (MPXV) has emerged as a pathogen that needs further study. Many non-endemic countries with no prior history of travel to an endemic region had increased global health concerns after the finding of MPXV cases in May 2022. Here, we summarize the clinical significance of MPXV and its unique infection characteristics. Finally, this review sheds light on worries regarding its resurgence in global health.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
