Monofunctionalized Gold Nanoparticles: Fabrication and Applications

Abstract

An overview of various approaches to synthesize gold nanoparticles (AuNPs) bearing one single chemically addressable unit and their diverse fields of application is presented. This comprehensive review not only describes the strategies pursued to obtain monofunctionalized AuNPs, but also reports their behavior as 'massive' molecules in wet chemical protocols and the scope of their applications. The latter reaches from site-specific labels in biomolecules over mechanical barriers in superstructures to building blocks in hybrid nano-architectures. The complementing physical properties of AuNPs combined with precise chemical control of their attachment makes these objects promising building blocks for numerous proof-of-concept experiments and applications.

Monoalkyl Phosphinic Acids as Ligands in Nanocrystal Synthesis

“…2,9 Despite the crucial role of ligands, it is striking that most colloidal synthesis methods use the same types of surfactants: oleic acid, oleylamine and octadecylphosphonic acid being the most common. While thiols are great ligands for metals, 12 and metal chalcogenides, 13 they are not thermally stable. Indeed, they are often used as sulphur precursors.…”

An organic cage controlling the dimension and stability of gold nanoparticles

“…Furthermore, the exposed triisopropylsilyl (TIPS)-protected terminal alkyne may act as a functional group, such that monofunctionalized Au NPs are expected. 44 …”

“…Furthermore, the exposed triisopropylsilyl (TIPS)-protected terminal alkyne may act as a functional group, such that monofunctionalized Au NPs are expected. 44 The synthesis of the cage target structure 1 is displayed in Scheme 1. The assembly of the central benzylic tribromide 7 bearing a lengthy OPE was already reported.…”