Mononeuritis multiplex complicating Henoch‐Schonlein purpura

Campbell, Scott; Hawley, Carmel M.; Staples, Christopher

doi:10.1111/j.1445-5994.1994.tb01767.x

Cited by 6 publications

(5 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Peripheral neuropathy involving facial, ulnar, femoral, sciatic, and peroneal nerves has been described in HSP [1,[8][9][10]. Mechanical compression due to local edema and joint effusion may cause peripheral neuropathy [10]. Since our patient had neither joint effusion nor local edema during his second attack, vasculitic involvement and ischemia probably resulted in a transient neuropathy of the tibial nerve.…”

Section: Discussionmentioning

confidence: 89%

See 1 more Smart Citation

Ataxia and peripheral neuropathy: rare manifestations in Henoch-Schönlein purpura

Bulun

Topaloğlu²,

Düzova³

et al. 2001

Pediatr Nephrol

View full text Add to dashboard Cite

Henoch-Schönlein purpura (HSP) is a multisystemic vasculitis. Nervous system involvement is usually underestimated. Headaches, mental status changes and seizures are the most frequent neurologic symptoms. Ataxia and mononeuropathy are both very rare. We present an 11-year-old boy with HSP who suffered from ataxia during the initial presentation and peripheral neuropathy at the time of a relapse. Brainstem vasculitic involvement was shown by magnetic resonance imaging, while cranial tomography was normal. All the neurologic symptoms and signs resolved following bolus methylprednisolone administration. Ten months later he had a second course of HSP with skin and renal involvement. A percutaneous renal biopsy, which was performed due to persistent hematuria, revealed mesangial proliferation with IgA deposition. During that period the patient experienced pain and numbness in the right foot and leg; electromyography showed signs of mononeuritis multiplex involving the right posterior tibial nerve. The patient responded to steroid therapy.

show abstract

Section: Discussionmentioning

confidence: 89%

“…MRI findings also confirmed vasculitic involvement of the central nervous system. Peripheral neuropathy involving facial, ulnar, femoral, sciatic, and peroneal nerves has been described in HSP [1,[8][9][10]. Mechanical compression due to local edema and joint effusion may cause peripheral neuropathy [10].…”

Section: Discussionmentioning

confidence: 99%

Ataxia and peripheral neuropathy: rare manifestations in Henoch-Schönlein purpura

Bulun

Topaloğlu²,

Düzova³

et al. 2001

Pediatr Nephrol

View full text Add to dashboard Cite

show abstract

“…However, PNS involvement has been documented as neuropathies of the brachial plexus and facial, peroneal, femoral and ulnar nerve, and in addition, Guillain–Barre syndrome and mononeuritis multiplex (78). Rare cases of IgAV-induced neurological manifestations have been reported in adult patients as ischemic stroke, axonal sensorimotor polyneuropathy (79, 80), mononeuritis multiplex (81, 82), acoustic neuritis, facial nerve palsy (83), intracerebral hemorrhage (84), anterior ischemic optic neuropathy (85), focal seizures (86), and encephalopathy (87).…”

Section: Medium-vessel Vasculitismentioning

confidence: 99%

Neurological Involvement in Primary Systemic Vasculitis

2019

View full text Add to dashboard Cite

Primary systemic vasculitis can affect every structure in both the central and peripheral nervous system, causing varied neurological manifestations of neurological dysfunction. Early recognition of the underlying causes of the neurological symptoms can facilitate timely treatment and improve the prognosis. This review highlights the clinical manifestations of primary systemic vasculitis in the nervous system.

show abstract

“…A biopsy showing predominant IgA deposition was performed in 31 (57%) of the 54 patients (7, 9, 10, 12, 14-16, 19, 20, 22, 23, 25, 26, 28, 29, 31, 32, 35, 37-39, 43-47, 50, 51, 53, 61 and 62): skin biopsy (n ¼ 15), renal biopsy (n ¼ 11), both skin and renal biopsy (n ¼ 5). Testing for IgG ANCA was negative in 14 patients with this examination (6,8,12,19,20,25,29,32,35,43,45,51,53,54).…”

Section: Methodsmentioning

confidence: 83%

“…In two of the aforementioned 37 cases [12,41], a concurrent involvement of the peripheral nervous system was noted. In 15 further cases of Henoch-Scho¨nlein syndrome, which were reported between 1970 and 2009, a cranial or peripheral neuropathy without severe hypertension and without any CNS dysfunction was noted [9,[43][44][45][46][47][48][49][50][51][52][53][54][55][56].…”

Section: Methodsmentioning

confidence: 99%