Morbidities, concordance, and predictors of preterm premature rupture of membranes among pregnant women at the University of Nigeria Teaching Hospital (UNTH), Enugu, Nigeria

Okeke, TC; Enwereji, JO; Adiri, CO; Onwuka, CI; Iferikigwe, ES

doi:10.4103/1119-3077.181361

Cited by 14 publications

(17 citation statements)

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“…However, the results of this study indicate that the number of group parity with PROM is not significantly different from the number of group parity without the KPD. 8 The results of this study are consistent with the research findings by Patil et al, where the occurrence of primigravids with PROM was 53 cases out of 100 births, compared to primigravids without PROM; 52 cases out of 100 cases -which is not significantly different. 10 This shows that the characteristics of subjects are based on maternal age, gestational age, and parity is a risk factor that causes rupture of the membranes in this study.…”

Section: Discussionsupporting

confidence: 92%

The low level of plasma vitamin C as a risk factor of preterm premature rupture of membrane

Sitepu¹,

Suwiyoga²,

Kusuma³

et al. 2020

Intisari Sains Medis

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Introduction: Preterm premature rupture of membrane (PPROM) still becomes a problem related with perinatal morbidity and mortality which is caused by multifactorial risk factor; especially strength of foetal membrane. Collagen is the main component of foetal membraneâ€™s extracellular matrix whereas plasma vitamin C roles as a collagen biosynthesis enzyme-dependent co-factor, down-regulator activity of MMP-1, MMP-2, and MMP-9 and also as antioxidant in remodelling and preventing structural damage extracellular matrix. The purpose of this study is to prove the low plasma level of vitamin C as a risk factor for PPROM on preterm pregnancy.Method: This study was an analytical observational unpaired case-control performed from March 23rd until August 23rd 2018 at Polyclinic and Emergency Unit of Obstetrics and Gynaecology Sanglah Central General Hospital, Buleleng General Hospital, Mangusada General Hospital, Sanjiwani General Hospital, Wangaya General Hospital, and Prodia Clinical Laboratory Denpasar. The samples were preterm pregnancy women with premature rupture of membrane (PROM) as a case group and without premature rupture of membrane as a control group. The samples were taken from peripheral venous blood and level of plasma vitamin C is measured by HPLC method. The data were analysed by SPSS for Windows 20.0 version program then presented as table and narrative.Result: Forty subjects were divided into 2 groups, 20 preterm pregnancy with PROM as a case group and 20 preterm pregnancy without PROM as a control group. Characteristic subject based on maternal age, gestational age, parity of both groups was 27.4 and 26.1 years old, 31 and 31 weeks, and also 1 and 1 time (p>0.05), not significantly different. The mean level of plasma vitamin C on case and control group were 3.90 Â± 1.61 dan 9.24 Â± 2.31 mg/L (p=0.001). On the case group the low level of plasma vitamin C was 51 times (OR= 51; CI 95% = 7.57â€“343.73; p=0,001) higher than the control group.Conclusion: The low level of plasma vitamin C is a risk factor of PPROM.

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Section: Discussionsupporting

confidence: 92%

The low level of plasma vitamin C as a risk factor of preterm premature rupture of membrane

Sitepu¹,

Suwiyoga²,

Kusuma³

et al. 2020

Intisari Sains Medis

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“…Preterm pre-labour rupture of the fetal membranes (PPROM) is rupture of the fetal membranes prior to 37weeks gestation. PPROM complicates 3% to 8% of all pregnancies [1,2] and is responsible for 20-30% of all preterm births [1] with attendant high perinatal mortality rate of about 54% [3].…”

Section: Introductionmentioning

confidence: 99%

Microbiological Pattern in Preterm Prelabour Rupture of the Fetal Membranes in South-Western Nigeria

Adewumi¹

2017

OGIJ

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Background: Preterm prelabour rupture of the fetal membranes (PPROM) complicates 3% to 4% of all pregnancies. It is responsible for 40% of all preterm births with its attendant high perinatal morbidity and mortality.Objective: The aim of this study was to determine the prevalence of PPROM; with profile and antibiotic susceptibility of isolated organisms.Methodology: It was a prospective study carried out between 10th July 2011 and 22nd August 2012 among recruited pregnant women that met the inclusion criteria. Collection of samples from the endocervix and posterior vaginal fornix by sterile speculum examination was done; with same processed using standard microbiological techniques.Results: Klessiella was the commonest organism isolated accounting for 32.1%, followed by Escherichia coli (19.6%); with highest sensitivity shown to ciprofloxacin (96.3%), and followed by amoxiclav (94.4%), ceftriazone (92.6%) and cefuroxime (90.6%). Conclusion:Prophylactic use of antibiotics in the management of PPROM should largely be based on the demonstrated microbiological pattern and sensitivity in the environment in question.

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“…Antenatal care is offered to pregnant women at the antenatal clinic on a daily basis from Monday to Friday. Further details of the antenatal clinic and attendance are as in previous studies [8][9][10]. All consenting pregnant women attending the antenatal clinic within the study period were consecutively recruited for the study using a convenient sampling method.…”

Section: Methodsmentioning

confidence: 99%

Pregnant women utilization of dental services: still a challenge in low resource setting

Onwuka

Iloghalu

et al. 2021

BMC Oral Health

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Background Poor oral health in pregnancy can be associated with poor pregnancy outcome, however, dental consultation among pregnant women appears to be low. Methods This was a questionnaire-based study of 413 women who attended the antenatal clinic of University of Nigeria Teaching Hospital (UNTH), Ituku/Ozalla, Enugu. The information obtained was analyzed using SPSS version 22. A p-value of less than 0.05 was considered statistically significant. Results Only 36 (8.7%) of the respondents had dental consultations in index pregnancy for complaints such as tooth ache and decay (66.7%) and pain as well as swelling of the gum (33.3%). The most common reason given for not visiting a dentist during the index pregnancy was the visit not being relevant to their pregnancy outcome (69.2%). After counseling them, only 249 (60.3%) agreed to have dental consultation during subsequent pregnancies. The relationship between visiting the dentist and place of residence (< 0.001), occupation (0.019) and frequency of brushing/ changing of brush (0.005, < 0.001 respectively) were statistically significant. Conclusion The prevalence of dental consultation during pregnancy is very low. Pregnant women should be encouraged to have routine dental consultation with oral health counseling and check-up incorporated as part of routine antenatal care.

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Morbidities, concordance, and predictors of preterm premature rupture of membranes among pregnant women at the University of Nigeria Teaching Hospital (UNTH), Enugu, Nigeria

Abstract: PPROM is a major complication of pregnancies and an important cause of perinatal morbidity and mortality. Management of these morbidities associated with PPROM poses a great challenge. However, women should be informed of these complications.

Cited by 14 publications

References 1 publication

The low level of plasma vitamin C as a risk factor of preterm premature rupture of membrane

The low level of plasma vitamin C as a risk factor of preterm premature rupture of membrane

Microbiological Pattern in Preterm Prelabour Rupture of the Fetal Membranes in South-Western Nigeria

Pregnant women utilization of dental services: still a challenge in low resource setting

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