Morbidity And Quality Of Life Among Head And Neck Cancer Patients Treated With Radical Radiotherapy

Abstract

Objectives:To determine the relative frequency of acute radiation morbidity and their perceived effect on quality of life among head and neck cancer patients treated with radical radiotherapy. Design: A cross-sectional study. Setting: Kenyatta National Hospital, Nairobi. Subjects: Thirty eight patients comprising 28 males and 10 females with ages ranging between 21 and 69 years were evaluated. Results: Most of the tumours occurred in the nasopharynx (38.6%). The rest of the tumours were equally divided between the oral cavity and larynx (31.6%). All tumours except two were carcinomas. The two exceptions were a glomus tumour and a malignant melanoma. The patients had received doses of radiotherapy ranging between 58.5 Grey and 75.5 Grey. Of the 38 patients, 22 (53%) completed their treatment in the prescribed time while 16 (47%) had treatment interruption on account of radiation morbidity. The cumulative radiation done at the time of interruption ranged between 20 and 46 Grey. The most frequent symptom was dryness of the mouth while the most troublesome symptom was difficulty in tasting foods. The quality of life (QOL) did not vary by age, gender or tumour site. Patients who had treatment interruption had a better QOL than those who did not. Conclusion:This study provides information that should aid in communicating with the head and neck cancer patients scheduled for radiotherapy and in the design of preventive and interventional strategies aimed at enhancing patient support and rehabilitation.

Treatment interruption among head and neck cancer patients undergoing radical radiotherapy

“…A treatment regime that results in frequent and/or severe tissue reactions adversely affects compliance as more patients are likely to require prolonged rest days (6). In an earlier study it was found that patients attending radiotherapy for head and neck tumours at the KNH radiotherapy unit suffered frequent and severe radiation morbidity (23). This may explain, at least in part, the frequent and prolonged duration of treatment interruptions in this study.…”

Morbidity of different treatment modalities in advanced Carcinoma larynx

“…Among the 10 cases of 3(30%) patients received radiotherapy after surgery for locoregional treatment and all the patient developed several side effect of radiotherapy like dryness of mouth and throat, loss of taste sensation, pigmentation of skin and subcutaneous fibrosis during study period (table-XI). Another study reveals the same type of morbidity of acute radiation like difficulty in tasting food 76.3%, dryness of mouth 92% 25 and taste changes and dry mouth 26 .…”