More effects of extracorporeal magnetic innervation and terazosin therapy than terazosin therapy alone for non-inflammatory chronic pelvic pain syndrome: a pilot study

Abstract

The objective of this study was to evaluate whether extracorporeal magnetic innervation (ExMI) combined with a-blocker therapy is more effective than a-blocker monotherapy for patients with non-inflammatory chronic prostatitis (CP)/chronic pelvic pain syndrome (CPPS), category IIIB. Patients were randomized to either terazosin monotherapy (group 1, n ¼ 21) or terazosin combined with ExMI therapy (group 2, n ¼ 19). Patients in group 2 had 12 treatment sessions of ExMI twice a week during 6 weeks. None of the patients experienced any side effects from treatment. The changes in each domain of the National Institutes of Health (NIH)-Chronic Prostatitis Symptom Index (CPSI) measured on week 6 were not significantly different between the groups. However, the difference (median, 25-75th percentiles) between the two groups in total NIH-CPSI scores was À4 (À11.5, À2) for group 1 and À12 (À17.3, À2.3) for group 2, respectively (P ¼ 0.047). At 6 weeks, 47.6% (10 of 21) of group 1 had a 425% decrease in total NIH-CPSI compared with 78.9% (15 of 19) of group 2 (P ¼ 0.041). Also, more patients in group 2 (78.9%) were rated as responders with a 6-point decrease in NIH-CPSI compared with group 1 (47.6%) (P ¼ 0.041). The early results suggest that ExMI combined with a-blocker therapy has better effect than a-blocker monotherapy for the treatment of CP/CPPS.

Therapeutic Intervention for Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS): A Systematic Review and Meta-Analysis

“…[8] While all 35 studies were randomized, only 14[18], [22]–[24], [26], [29]–[34], [43]–[45] were categorized as randomized appropriately on the Jadad system (Table S3). Of the 35 randomized studies, 21[18]–[24], [26]–[37], [44], [50] were blinded and 19[18]–[24], [26], [28], [30]–[37], [44], [50] were blinded appropriately.…”

Minimally Invasive Therapies for Chronic Pelvic Pain Syndrome

“…The mean symptom scores decreased significantly in the actively treated group at 3 months and 1 year (P<0.05); the greatest improvement was in pain-related symptoms [77]. In 2006, Paick et al [78] showed that extracorporeal magnetic innervation combined with α-blocker therapy may be more effective than α-blocker monotherapy for patients with CP/CPPS.…”

Update on minimally invasive therapy for chronic prostatitis/chronic pelvic pain syndrome

“…Paick et al [ 16 ] combined extracorporeal magnetic innervation (ExMI) with α -blocker therapy (group 1; n = 21) to determine if it were more effective than α -blocker monotherapy (group 2; n = 19) for patients with CPPS (category IIIb). Patients in group 2 had 12 treatment sessions of ExMI for 6 weeks.…”