More Favorable Outcomes with Peptic Ulcer Bleeding Due to Helicobacter Pylori

Chason, Rebecca D.; Reisch, Joan; Rockey, Don C.

doi:10.1016/j.amjmed.2013.02.025

Cited by 8 publications

(8 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, many otherwise beneficial therapies, including low-dose aspirins, dual anti-platelet therapy and nonsteroidal anti-inflammatory drugs (NSAIDs) such as indomethacin, have been shown to be important risk factors for recurrent ulcers and related complications [61]. It has been reported that about 25% of gastric ulcers are caused by NSAIDs [11]. NSAIDs are widely used for pain control and prevention of malignancies, strokes, pre-eclampsia, Alzheimer's disease, etc.…”

Section: Introductionmentioning

confidence: 99%

Quercetin attenuates, indomethacin-induced acute gastric ulcer in rats

Al-Kushi

ElSawy

2017

Folia Morphol

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Quercetin attenuates, indomethacin-induced acute gastric ulcer in rats

Al-Kushi

ElSawy

2017

Folia Morphol

View full text Add to dashboard Cite

show abstract

“…Eliminating one independent risk factor can attenuate the effect of another independent factor on inducing peptic ulcer bleeding. A recent study found that patients with bleeding peptic ulcers and concurrent Hp infection have a more favorable outcome than those without [129]. …”

Section: Resultsmentioning

confidence: 99%

Diagnosis, Treatment, and Outcome in Patients with Bleeding Peptic Ulcers andHelicobacter pyloriInfections

Huang

Lee

2014

BioMed Research International

View full text Add to dashboard Cite

Upper gastrointestinal (UGI) bleeding is the most frequently encountered complication of peptic ulcer disease. Helicobacter pylori (Hp) infection and nonsteroidal anti-inflammatory drug (NSAID) administration are two independent risk factors for UGI bleeding. Therefore, testing for and diagnosing Hp infection are essential for every patient with UGI hemorrhage. The presence of the infection is usually underestimated in cases of bleeding peptic ulcers. A rapid urease test (RUT), with or without histology, is usually the first test performed during endoscopy. If the initial diagnostic test is negative, a delayed 13C-urea breath test (UBT) or serology should be performed. Once an infection is diagnosed, antibiotic treatment is advocated. Sufficient evidence supports the concept that Hp infection eradication can heal the ulcer and reduce the likelihood of rebleeding. With increased awareness of the effects of Hp infection, the etiologies of bleeding peptic ulcers have shifted to NSAID use, old age, and disease comorbidity.

show abstract

“…43 H.pylori infection and the use of nonsteroidal anti-inflammatory drugs (NSAIDs) or a combination of the two are the leading causes of peptic ulcers in developing countries. 12,27,44,45 H.pylori infection has been shown to cause duodenal ulcers and about two-thirds of causing gastric ulcers. 14,45 H.pylori with cagA, vacA, and babA positive strain pose a significant risk from developing peptic ulcers, especially duodenal ulcers.…”

Section: Peptic Ulcer Diseasementioning

confidence: 99%

“…12,27,44,45 H.pylori infection has been shown to cause duodenal ulcers and about two-thirds of causing gastric ulcers. 14,45 H.pylori with cagA, vacA, and babA positive strain pose a significant risk from developing peptic ulcers, especially duodenal ulcers. 10,[46][47][48][49] Meanwhile, gastric ulcers are related to the iceA1 and iceA2 genes.…”

Section: Peptic Ulcer Diseasementioning

confidence: 99%

Clinical and Endoscopic Features in Helicobacter Pylori Infection: Literature Review

Budiman

Bestari

Suryanti

2021

InaJGHE

View full text Add to dashboard Cite

Helicobacter pylori is a common infection worldwide and can cause functional dyspepsia, gastritis, and peptic ulcers, leading to gastric cancer. The very diverse clinical outcomes and symptoms of this infection are difficult to distinguish from one another. Endoscopy is one of the methods used to detect Helicobacter pylori infection. Still, it has various endoscopic features, has the possibility of false-negative results, and requires skill to get the maximum results.This study found that infection can cause various clinical manifestations due to different virulence factors of Helicobacter pylori bacteria. In functional dyspepsia, the patient's most common symptoms are epigastric pain, nausea, and vomiting. In gastritis, Helicobacter pylori infection often causes chronic gastritis with topographic features of pangastritis, and endoscopic features that are usually found are redness, swelling, and regular arrangement of collecting venules (RAC). The most common symptom in peptic ulcers is pain that occurs after eating or at night, and this infection can cause duodenal and gastric ulcers. Currently, the relationship between Helicobacter pylori infection and gastroesophageal reflux disease (GERD) is controversial. In gastric cancer, the most common symptoms are weight loss and repeated vomiting. This infection is more likely to causes intestinal-type gastric cancer.

show abstract

More Favorable Outcomes with Peptic Ulcer Bleeding Due to Helicobacter Pylori

Cited by 8 publications

References 32 publications

Quercetin attenuates, indomethacin-induced acute gastric ulcer in rats

Quercetin attenuates, indomethacin-induced acute gastric ulcer in rats

Diagnosis, Treatment, and Outcome in Patients with Bleeding Peptic Ulcers andHelicobacter pyloriInfections

Clinical and Endoscopic Features in Helicobacter Pylori Infection: Literature Review

Contact Info

Product

Resources

About