Morphologic changes of cancerous ascitic cells induced by anticancer drug therapy. Five cases reports of ovarian and endometrial cancers.

Intraperitoneally transplanted tumors implanted and began developing with ascites in about 62% of the female rats within 4 to 6 weeks after transplantation. The tumor used in this study was an adenocarcinoma and which originated from a primary ovarian cancer in rats of the same strain (Wistar). The morphology and biological behavior of the tumor were very similar to the tumor in humans. Moreover, the preliminary results with cisplatin therapy indicate that intraperitoneal cancer corresponding to stage lEE or N in the FIGO classification is a promising model for experimental therapeutic studies of common epithelial carcinoma at an advanced stage.

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An experimental model for advanced ovarian cancer.

Sugiyama

Nishida

Yokota

et al. 1990

Kurume Med. J.

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Morphologic changes of cancerous ascitic cells induced by anticancer drug therapy. Five cases reports of ovarian and endometrial cancers.

Abstract: Ovarian cancer-Endometrial cancer-Anticancer drugs-Ascites fluid-Cytology Morphologic changes of cancerous ascitic cells induced by anticancer drug therapy-Five cases reports of ovarian and endometrial cancers-Masahiro OKAWADA1),

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An experimental model for advanced ovarian cancer.

An experimental model for advanced ovarian cancer.

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