Morphologic study of the cornea by in vivo confocal microscopy and optical coherence tomography after bifocal refractive corneal inlay implantation

Malandrini, Alex; Martone, Gianluca; Canovetti, Annalisa; Menabuoni, Luca; Balestrazzi, Angelo; Fantozzi, Chiara; Lenzetti, Chiara; Fantozzi, Marco

doi:10.1016/j.jcrs.2013.08.057

Cited by 15 publications

(15 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the creation of intrastromal ring tunnels, Kamburoglu et al [16] observed that the resection created by FSL was deeper by 6.5-69 lm in a Scheimpflug camera observation. Recent assessment with AS-OCT showed that FSL resections with an intended depth of 300 lm were created at 292 ± 10 lm [17]. In the current case series, the mean incision depth was deeper by 60 lm.…”

Section: Discussionmentioning

confidence: 50%

See 1 more Smart Citation

Clinical utility of femtosecond laser-assisted astigmatic keratotomy after cataract surgery

et al. 2015

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 50%

“…The technology has been used to create LASIK corneal flaps [4], corneal tunnels for intrastromal rings [16,17], and grafts for PKP [5]. Accurate incisions were anticipated for the FSL-assisted AK incisions.…”

Section: Discussionmentioning

confidence: 99%

Clinical utility of femtosecond laser-assisted astigmatic keratotomy after cataract surgery

et al. 2015

View full text Add to dashboard Cite

show abstract

“…When the inlay is removed, the patient’s visual acuity returns to ranges comparable to the preoperative state 11,15,16. In the FDA clinical trials, 15 (3%) patients had their inlay removed at 12 months, 36 (7%) at 24 months, and 44 (8%) at 36 months.…”

Section: Discussionmentioning

confidence: 99%

Six-month visual outcomes for the correction of presbyopia using a small-aperture corneal inlay: single-site experience

Moshirfar¹,

Quist²,

Skanchy³

et al. 2016

OPTH

View full text Add to dashboard Cite

ObjectiveThe objective of this study was to describe 6-month postoperative efficacy and safety outcomes after monocular KAMRA corneal inlay implantation in emmetropic presbyopic patients.Study designThis study followed a retrospective chart analysis.SettingThis study was performed at Hoopes Vision in Draper, UT, USA.Subjects and methodsFifty-seven patients met the inclusion criteria of this study and underwent KAMRA corneal inlay implantation following the approval of the United States Food and Drug Association between May 2015 and April 2016 at a single site. Surgery involved femtosecond laser-created corneal pockets of various depths. Efficacy, safety, and patient satisfaction reports were analyzed at 3 and 6 months.ResultsAt 6 months follow-up, the monocular uncorrected near visual acuity (UNVA) was Jaeger (J) 4 (20/32), the mean uncorrected distance visual acuity was 20/25, and the mean corrected distance visual acuity was 20/20. At 6 months, 71% of patients with a pocket depth of ≥250 μm had a UNVA of 20/20 or better, whereas only 22% of patients with a shallow pocket depth of <250 μm had a UNVA of 20/20 or better. There was no statistical difference in UNVA at 6 months between virgin eyes and post-LASIK eyes. One patient had an explant and five patients underwent inlay recentration, all of which resulted in improved visual acuity. At 6 months, 72% of patients reported some level of satisfaction, 26% of patients reported being “not dependent” on reading glasses, and 62% of patients reported being able to do most things in bright light without reading glasses.ConclusionFor patients with emmetropic presbyopia, the KAMRA inlay is a viable treatment option resulting in improved UNVA. Increased pocket depth may be associated with better postoperative outcomes. Safety rates are high, while explantation and recentering rates are low. Overall, patient satisfaction of the KAMRA inlay is good.

show abstract

“…Furthermore, these three patients underwent concurrent LASIK, which could possibly affect the integrity of the cornea to a greater degree than the creation of a femtosecond tunnel, making them more susceptible to dry eye and infection. It is also possible that the use of preoperative topical antibiotic may help confer a lower postoperative infection rate; Malandrini et al ,18 in their use of the Flexivue Microlens inlay, describe the use of levofloxacin (0.5%) and tobramycin (0.3%)/dexamethasone (0.1%) four times a day for 1 day prior to surgery. It has been suggested that soaking biocompatible implants in antibiotic prior to insertion may help to reduce the incidence of infection and this is common practice in other subspecialties such as with the use of orbital implants 28 29.…”

Section: Discussionmentioning

confidence: 99%

Corneal inlay implantation complicated by infectious keratitis

et al. 2015

View full text Add to dashboard Cite

Infectious keratitis can occur at an early or late stage following corneal inlay implantation. Final visual acuity can be limited by stromal scarring; in the cases where the infiltrate was small and off the visual axis at the time of presentation, the final visual acuity was better than those patients who presented with larger lesions affecting the visual axis. Though infection may necessitate removal of the inlay, early positive response to treatment may enable the inlay to be left in situ.

show abstract

Morphologic study of the cornea by in vivo confocal microscopy and optical coherence tomography after bifocal refractive corneal inlay implantation

Abstract: Dr. M. Fantozzi is a member of the Presbia medical advisory board. No other author has a financial or proprietary interest in any material or method mentioned.

Cited by 15 publications

References 28 publications

Clinical utility of femtosecond laser-assisted astigmatic keratotomy after cataract surgery

Clinical utility of femtosecond laser-assisted astigmatic keratotomy after cataract surgery

Six-month visual outcomes for the correction of presbyopia using a small-aperture corneal inlay: single-site experience

Corneal inlay implantation complicated by infectious keratitis

Contact Info

Product

Resources

About