Morphological aspects of the pancreas in the rat and the rabbit: an investigation into the location, ducts, arteries and veins

Abstract

The aim of the present study was to determine both the location of the pancreatic duct and the anatomical variation in the pancreatic ducts of rat and rabbit. Following administration of ether anesthesia, the abdomens were opened. Catheters were placed in the ileocolic vein, junction of the duodenum and jejunum, and into the aorta. All arteries, veins and pancreatic ducts were filled with red, blue and white dyed latex, respectively. The rat pancreas was consisted of three lobes, while the rabbit pancreas was consisted of two lobes. The rat pancreas also involved a diffuse gland situated in the gastrolienal ligament and mesoduodenum. It was observed two major ducts which name posterior pancreatic duct, anterior pancreatic ducts. The ducts that were determined in the right side of the biliaropancreatic duct open from origin the biliaropancreatic duct were measurements 8.09+2.65 mm right side and left side 7.32+3.61 mm. The rabbit pancreas included a diffuse gland situated among the liver, stomach and duodenum. In the rabbit, the duct of the pancreas (pancreatic duct) entered the duodenum 51.52+3.23cm distal to the pylorus. Bunting & Jones (19) reported that the pancreatic duct opened to the duodenum and 25-27cm away from (distal part) the pylorus in rabbit, the present authors found the pancreatic duct opened to the duodenum and measured 46.33-57.17cm in our study. Tavşan ve rat pankreas'ının morfolojik görünümü: Lokalizasyonu, kanalları, arterleri ve venleri üzerine bir araştırma ÖZ Bu çalışmanın amacı rat ve tavşanlarda ductus pancreaticus'un yerleşimini ve bu türlerde ductus pancreaticus'un anatomik varyasyonlarını belirlemektir. Eter anestezi uygulaması sonrası cavum abdominis açıldı. Kateter, vena iliecolica, duodenum ile jejenumun birleşim noktasına ve aorta'ya yerleştirildi. Tüm arter, ven ve pancreas kanalları sırasıyla kırmızı mavi ve beyaz boyalı lateks ile dolduruldu. Rat pankreası üç, tavşan pankreası ise iki lobdan oluşmaktaydı. Rat pankreası ligamentum gastrolienal ve mesoduodenum arasında yaygın bir bez olarak görüldü. Ductus pancreaticus anterior ve posterior olmak üzere iki kanal olduğu gözlendi. Bu kanalların başlangıcından itibaren sağ tarafta 8.09+2.65 mm sonra, sol tarafta da 7.32+3.61 mm sonra ductus biliopancreaticus'a açıldığı saptandı. Tavşan pankreası karaciğer, mide ve duodenum arasında yaygın bir bez olarak görülmekteydi. Tavşanda ductus pancreaticus, distal pylorus'ten 51.52+3.23 cm uzaklıkta duodenum'a açılır. Bunting & Jones (19) tarafından ductus pancreaticus'un tavşanda pylorus'un başlangıcından 25-27 cm sonra duodenum'a açıldığı bildirilmiştir. Bu çalışmada ise ductus pancreaticus'un açılış deliğinin pylorus'a uzaklığı 46.33-57.17cm olarak ölçüldü.

Morphological study of the pancreatic duct system in chinchilla (Chinchilla laniger Molina).

“…The anatomical structure of the chinchilla pancreas is comparable to what has been described for the rabbit (7), in which the same division into three lobes has been observed. The human pancreas is a compact organ that is protected from severe trauma by being located close to the back wall of the abdominal cavity.…”

“…Previous investigations have looked at the anatomy of pancreatic ducts and the location of their outlet in relation to duodenal papillae. In the rat, several pancreatic ducts open to the common bile duct at various points, but before entering the duodenum at the duodenal papilla (7,10). The minor duodenal papilla is absent in rats, so the distal segment of the common bile duct contains a mixture of liver and pancreatic secretions (33).…”

A Novel Method for Establishing a Rabbit Model of Diabetic Periarthritis: The Combination of Alloxan and a Continuous Strain with Ice Compression

“…Harvesting of the pancreas: Access to the pancreas was achieved by opening the rabbit's abdominal cavity, where the pancreas, distinguished by its crescent-shaped, dark red appearance, was separated from the spleen and the duodenal region. The harvested pancreas, characterized by its pink color and dispersed irregular glands, was xed in a 4% paraformaldehyde solution for subsequent analysis (Haligur et al, 2018;Toledo-Pereyra, 1988). Euthanasia: After anesthesia, the rabbits were humanely euthanized by intracardiac injection of air to ensure swift and painless death.…”

The role of resveratrol in hepatotoxicity caused by methotrexate

“…Rsv has been studied for a several decades in different therapeutic research areas and epidemiological studies have observed the relationship between consumption of Rsv and healthy (16,17). Laboratory animals are used in many experimental studies (18)(19)(20)(21). In numerous experimental studies reported that resveratrol possesses many bioactivities and has beneficial for healthy like antioxidant, anti-inflammatory, improving diseases and also has a hepatoprotective effect (22,23).…”