Morphology and Thermal Properties of Core-Shell PVA/PLA Ultrafine Fibers Produced by Coaxial Electrospinning

Gonçalves, Raquel; Silva, Flavia F. F. da; Picciani, Paulo H. S.; Dias, Marcos L.

doi:10.4236/msa.2015.62022

Cited by 14 publications

(12 citation statements)

References 29 publications

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“…The initial weight loss (2.3%) occurred below 80 C was attributed to the remaining solvent in the PLA fibers. The main weight loss appeared between 220 C and 355 C with degradation peak at around 346 C, which is consistent with the study of Gonçalves, da Silva, Picciani, and Dias (2015) who attributed this degradation to chain scission. The TGA curves for PLA fibers with carvacrol also showed two weight loss stages.…”

Section: Polymersupporting

confidence: 91%

Carvacrol loaded electrospun fibrous films from zein and poly(lactic acid) for active food packaging

2018

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The composite fibrous films were developed from zein and poly(lactic acid) (PLA) by incorporating carvacrol at three different concentrations (5, 10 and 20%) using electrospinning. The morphology and size of fibers obtained from both zein and PLA were affected by the level of the incorporated carvacrol. The Fourier transform infrared (FTIR) spectroscopy and thermogravimetric analysis (TGA) results showed that carvacrol was encapsulated in electrospun zein and PLA fibers. The antioxidant activity of carvacrol loaded zein fibers ranged from 62 to 75%, while antioxidant capacity of PLA fibers varied from 53 to 65% for 5e20% carvacrol content. The composite fibrous films showed a sustained diffusion controlled release behavior. Preliminary studies on whole wheat bread samples showed that carvacrol loaded electrospun zein and PLA fibers are able to preserve bread samples, indicating that they are good candidates for active food packaging applications to extend the shelf life of whole wheat bread.

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Section: Polymersupporting

confidence: 91%

Carvacrol loaded electrospun fibrous films from zein and poly(lactic acid) for active food packaging

2018

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“…Also, the topographical and biochemical cues that promote tissue healing can be provided. Raquel et al obtained core–shell PVA/PLA ultrafine fibers by coaxial electrospinning, and the hydrophilicity of pure fibers was improved obviously, indicating a good potential for use as biomaterials for the controlled release of bioactive molecules [30]. With reduced size and dimensionality, polymer nanofibers exhibit exceptional mechanical properties compared with those of their macroscopic counterparts, since the former one is better treated as a one-dimensional system.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Enhancement of Strength and Toughness of PLA Induced by Miscibility Variation with PVA

et al. 2018

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The mechanical properties of poly (lactic acid) (PLA) nanofibers with 0%, 5%, 10%, and 20% (w/w) poly (vinyl alcohol) (PVA) were investigated at the macro- and microscale. The macro-mechanical properties for the fiber membrane revealed that both the modulus and fracture strain could be improved by 100% and 70%, respectively, with a PVA content of 5%. The variation in modulus and fracture strain versus the diameter of a single electrospun fiber presented two opposite trends, while simultaneous enhancement was observed when the content of PVA was 5% and 10%. With a diameter of 1 μm, the strength and toughness of the L95V5 and L90V10 fibers were enhanced to over 3 and 2 times that of pure PLA, respectively. The structural evolution of electrospun nanofiber was analyzed by differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FTIR). Although PLA and PVA were still miscible in the concentration range used, the latter could crystallize independently after electrospinning. According to the crystallization behavior of the nanofibers, a double network formed by PLA and PVA—one microcrystal/ordered structure and one amorphous structure—is proposed to contribute to the simultaneous enhancement of strength and toughness, which provides a promising method for preparing biodegradable material with high performance.

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“…PVA shows the typical infrared bands of hydrocyl groups at 3200–3600 cm −1 which can not be seen in the core-shell structured nanofibers. This indicates that the PVA is not on the surface of the fibers, which is an additional proof of effective encapsulation in core-shell nanofibers [34]. After the PBS treatment, typical infrared bands of hydrocyl groups of PVA at 3200–3600 cm −1 were observed in the nanofibers and FTIR spectra of MH nanofiber are shown in Figure 4a as an example.…”

Section: Resultsmentioning

confidence: 99%

Controlled Release of Metformin Hydrochloride from Core-Shell Nanofibers with Fish Sarcoplasmic Protein

Sumeyra

Ulkugul

et al. 2019

Medicina

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Background and Objectives: A coaxial electrospinning technique was used to produce core/shell nanofibers of a polylactic acid (PLA) as a shell and a polyvinyl alcohol (PVA) containing metformin hydrochloride (MH) as a core. Materials and Methods: Fish sarcoplasmic protein (FSP) was extracted from fresh bonito and incorporated into nanofiber at various concentrations to investigate the influence on properties of the coaxial nanofibers. The morphology, chemical structure and thermal properties of the nanofibers were studied. Results: The results show that uniform and bead-free structured nanofibers with diameters ranging from 621 nm to 681 nm were obtained. A differential scanning calorimetry (DSC) analysis shows that FSP had a reducing effect on the crystallinity of the nanofibers. Furthermore, the drug release profile of electrospun fibers was analyzed using the spectrophotometric method. Conclusions: The nanofibers showed prolonged and sustained release and the first order kinetic seems to be more suitable to describe the release. MTT assay suggests that the produced drug and protein loaded coaxial nanofibers are non-toxic and enhance cell attachment. Thus, these results demonstrate that the produced nanofibers had the potential to be used for diabetic wound healing applications.

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Morphology and Thermal Properties of Core-Shell PVA/PLA Ultrafine Fibers Produced by Coaxial Electrospinning

Cited by 14 publications

References 29 publications

Carvacrol loaded electrospun fibrous films from zein and poly(lactic acid) for active food packaging

Carvacrol loaded electrospun fibrous films from zein and poly(lactic acid) for active food packaging

Simultaneous Enhancement of Strength and Toughness of PLA Induced by Miscibility Variation with PVA

Controlled Release of Metformin Hydrochloride from Core-Shell Nanofibers with Fish Sarcoplasmic Protein

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