Morphology development during sessile single droplet drying of mixed maltodextrin and whey protein solutions

Quantitative investigation of particle formation of a model pharmaceutical formulation using single droplet evaporation experiments and X-ray tomography

“…Groups have been using droplet drying experiments to investigate droplet shrinkage, [14] skin formation [15,16,17] and buckling phenomena of droplets undergoing drying. [18,19] Acoustic levitation provides a containerless environment for single droplet evaporation experiments with a minimised 2 risk for heterogeneous nucleation events and conductive heat transfer compared to similar experiments with individual droplets suspended on a filament. Quasi-stationary levitated droplets can be monitored to study liquid evaporation and particle formation processes.…”

“…The goal of XRT analysis is increasingly moving towards relating structure to the dynamics of solidification. [16,19] In this paper we demonstrate the investigation of particle formation processes using an acoustic levitator (SAL) and the subsequent structural characterisation with XRT.…”

Pulsed electric field pre-treatment for drying of living bacteria

“…From the onset of the skin formation, often referred to as the locking point, the particle morphology starts to develop (Both et al, 2018;Siemons et al, 2020a). In droplets with 20%…”

“…Spray drying can yield entirely distinct particle morphologies depending on the carrier matrix and the applied drying conditions (e.g. smooth, hollow, dented) (Both et al, 2018;Siemons et al, 2020a). Hitherto, particle morphology development during spray drying has been mainly studied with respect to physical powder properties such as bulk density and particle size (Both et al, 2018;Sadek et al, 2014;.…”

“…smooth, hollow, dented) (Both et al, 2018;Siemons et al, 2020a). Hitherto, particle morphology development during spray drying has been mainly studied with respect to physical powder properties such as bulk density and particle size (Both et al, 2018;Sadek et al, 2014;. Some studies suggested that the development of the skin and the overall particle morphology during spray drying may also affect bacterial survival (Ghandi et al, 2012b;Khem et al, 2016Khem et al, , 2015Wang et al, 2016).…”