Morphology, incidence of bridging, and dimensions of sella turcica in different racial groups

Muhammed, Fenik Kaml; Abdullah, Adil O.; Rashid, Zhwan Jamal; Pusic, Tamara; Shbair, Mohammed

doi:10.1007/s11282-018-0328-x

Cited by 16 publications

(32 citation statements)

References 26 publications

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“…A cephalometric morphometric study of the ST has long been investigated previously [1,2,24,34]. This retrospective study describes the morphological appearance, the incidence of bridging and linear dimensions of the ST in the Chinese and Nepalese subjects and identifies any possible race, age and gender group associated with a size of the ST. Radiographic diagnosis of the ST shape was chosen to match previous studies and classified into U-, J-, and flat-shapes [1,10,11,24,30]. In accordance with the present results, previous studies have demonstrated that a greater frequency of a U-and J-shaped ST has been observed in patients [10,11,30].…”

Section: Discussionmentioning

confidence: 99%

“…The selection criteria for these age-defined groups were according to the following multiple observations: (i) no significant alteration was observed in the morphology of the ST after 12 years of age [6], (ii) females completed their pubertal progress at roughly 15 years old [29], and (iii) roughly the same size of the ST were studied in young adult female and male, except during pregnancy [1,11,24,34]. Inclusion criteria: all subjects were clinically healthy, without major illnesses or medical conditions, and all class III patients were managed by orthodontics alone without surgical intervention.…”

Section: Methodsmentioning

confidence: 99%

“…Three types of the ST morphology was distinguished on radiographic: U-shaped, wherein the dorsum and tubercle of the ST are at the same height. J-shaped, wherein the dorsum sella is in a lower position in relation to the tubercle of the ST. Flat-shaped, when the depth of ST is minimal [10,11,24]. ST bridging was categorized into no calcification (normal), partially calcified, and completely calcified based on previous studies [20,24,28].…”

Section: Methodsmentioning

confidence: 99%

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A morphometric study of the sella turcica: race, age, and gender effect

Muhammed

Abdullah

2020

Folia Morphol

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Background:The aim of this study was to evaluate the morphological appearance, bridging incidence, and linear dimensions of sella turcica (ST) in Chinese and Nepalese individuals. Materials and methods: This retrospective study examined digital standardised lateral cephalometric of 360 Chinese and Nepalese subjects, which consisted of 116 females and 64 males with an age range of 8-28 years. The sella morphology, bridging, and size were assessed on the lateral cephalometric radiographs, and the data were correlated with race, gender, and age. Results: Sella turcica presented a normal morphology in most Nepalese (90%) subjects whereas flat-shaped morphology were highly prevalent among Chinese subjects (36.7%). The frequency of full bridging was 2.8% and 11.7% for Chinese and Nepalese subjects, respectively. When the race was compared with sella size, a statistically significant difference was detected in length (p < 0.05) and diameter (p < 0.001) of ST. A significant correlation was found between length and diameter of the ST and age in Chinese and Nepalese subjects. No significant correlation was observed between the size of ST and gender of Chinese and Nepalese subjects. The only parameter significantly associated with race, age and gender was the diameter of ST. Conclusions: These findings assist orthodontists, neurosurgeons, and forensic medical investigators to focus on the diameter of ST during orthodontic treatment planning, diagnosis of pathology of the pituitary gland, and age determination.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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A morphometric study of the sella turcica: race, age, and gender effect

Muhammed

Abdullah

2020

Folia Morphol

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“…Its morphology is often described subjectively and qualitatively, and it is classified into shapes such as circular, oval, flat, shallow, and J-shaped [ 17 ]. Several studies have examined the prevalence and distribution of different morphological presentations of the sella turcica in “normal” individuals to produce reference standards [ 2 , 15 , 17 - 19 ]. These reference standards assist in detecting deviations from the norm and pathology in the sella turcica [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Sella Turcica Morphology in Patients With Genetic Syndromes: Protocol for a Systematic Review

Roomaney

2020

JMIR Res Protoc

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Background The sella turcica is an important anatomical reference used in orthodontics and the evaluation of craniofacial growth. Studies have found an association between variations in sella turcica morphology in patients with certain syndromes affecting the craniofacial complex. It is hypothesized that each related syndrome or pathological condition is associated with a specific pattern of malformation of the sella turcica. Objective This study outlines the protocol for a systematic review that aims to determine if genetic syndromes involving the craniofacial complex are associated with abnormal radiographic sella turcica morphology and if there is a pattern of malformation that is consistent with each syndrome. Methods An electronic database search was conducted using a planned search strategy to identify relevant studies. We included primary studies evaluating the morphology of the sella turcica based on imaging from a lateral view. Specifically, only studies with postnatal human participants with genetic syndromes involving the craniofacial complex were included in this review. We placed no restrictions on the language or time frame of these studies. Based on the search findings, studies were further screened for relevance and eligibility by two independent reviewers. Data were extracted from the selected studies. We assessed the selected studies for risk of bias and quality by using risk of bias tools from the Joanna Briggs Institute. We will provide a narrative synthesis of our findings and a structured summary based on prespecified themes. Results The protocol is registered with PROSPERO (#CRD42019148060) and approved by the University of Western Cape Biomedical Science Research Ethics Committee (BM205/3). The literature search was conducted in September 2019 and updated in July 2020. The study was completed in August 2020, and the findings will be published in an open-access journal. Conclusions The results of this systematic review are expected to provide a comprehensive list of morphological variations of the sella turcica, which will aid in the identification of syndromes associated with the craniofacial complex. We also expect to identify patterns of sella turcica morphology that highlight genotype-phenotype correlations, thus adding to the body of evidence relating to genetics and craniofacial malformations. Trial Registration PROSPERO International Prospective Register of Systematic Reviews CRD42019148060; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=148060 International Registered Report Identifier (IRRID) RR1-10.2196/16633

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“…Its morphology is often described subjectively and qualitatively, and it is classified into shapes such as circular, oval, flat, shallow, and J-shaped [17]. Several studies have examined the prevalence and distribution of different morphological presentations of the sella turcica in "normal" individuals to produce reference standards [2,15,[17][18][19]. These reference standards assist in detecting deviations from the norm and pathology in the sella turcica [2].…”

Section: Introductionmentioning

confidence: 99%

Sella Turcica Morphology in Patients With Genetic Syndromes: Protocol for a Systematic Review (Preprint)

Roomaney¹

2019

Preprint

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BACKGROUND The sella turcica is an important anatomical reference used in orthodontics and the evaluation of craniofacial growth. Studies have found an association between variations in sella turcica morphology in patients with certain syndromes affecting the craniofacial complex. It is hypothesized that each related syndrome or pathological condition is associated with a specific pattern of malformation of the sella turcica. OBJECTIVE This study outlines the protocol for a systematic review that aims to determine if genetic syndromes involving the craniofacial complex are associated with abnormal radiographic sella turcica morphology and if there is a pattern of malformation that is consistent with each syndrome. METHODS An electronic database search was conducted using a planned search strategy to identify relevant studies. We included primary studies evaluating the morphology of the sella turcica based on imaging from a lateral view. Specifically, only studies with postnatal human participants with genetic syndromes involving the craniofacial complex were included in this review. We placed no restrictions on the language or time frame of these studies. Based on the search findings, studies were further screened for relevance and eligibility by two independent reviewers. Data were extracted from the selected studies. We assessed the selected studies for risk of bias and quality by using risk of bias tools from the Joanna Briggs Institute. We will provide a narrative synthesis of our findings and a structured summary based on prespecified themes. RESULTS The protocol is registered with PROSPERO (#CRD42019148060) and approved by the University of Western Cape Biomedical Science Research Ethics Committee (BM205/3). The literature search was conducted in September 2019 and updated in July 2020. The study was completed in August 2020, and the findings will be published in an open-access journal. CONCLUSIONS The results of this systematic review are expected to provide a comprehensive list of morphological variations of the sella turcica, which will aid in the identification of syndromes associated with the craniofacial complex. We also expect to identify patterns of sella turcica morphology that highlight genotype-phenotype correlations, thus adding to the body of evidence relating to genetics and craniofacial malformations. CLINICALTRIAL PROSPERO International Prospective Register of Systematic Reviews CRD42019148060; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=148060 INTERNATIONAL REGISTERED REPORT RR1-10.2196/16633

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Morphology, incidence of bridging, and dimensions of sella turcica in different racial groups

Cited by 16 publications

References 26 publications

A morphometric study of the sella turcica: race, age, and gender effect

A morphometric study of the sella turcica: race, age, and gender effect

Sella Turcica Morphology in Patients With Genetic Syndromes: Protocol for a Systematic Review

Sella Turcica Morphology in Patients With Genetic Syndromes: Protocol for a Systematic Review (Preprint)

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