Morphometric MRI Study of the Brain Ventricles in Healthy Turkish Subjects

Abstract

POLAT, S.; ÖKSÜZLER, F. Y.; ÖKSÜZLER, M.; KABAKCI, A. G. & YÜCEL, A. H. Morphometric MRI study of the brain ventricles in healthy Turkish subjects. Int. J. Morphol., 37(2):554-560, 2019. SUMMARY:The aim of this study was to determine the normal values of brain ventricles and indices in healthy subjects in our population using magnetic resonance imaging (MRI) and to reveal sex and age related differences. The MRI of two hundred-sixty-five healthy individuals aged between eighteen and eighty-seven years were examined and the midsagittal and axial images were used for measurements. The measurements were performed from MRI on a Workstation. The following mean values of brain ventricles and indices were observed; frontal horn width (FHW) (33.14 mm); third (3rd) ventricle width (TVW) (3.37 mm); fourth ventricle anteroposterior width (FVWAP) (9.93 mm); fourth ventricle transverse width (FVWT) (12.40 mm); and the maximum transverse inner diameter of the skull (TIDS) (128.75 mm) in females. The same dimensions were 34.85 mm, 3.91 mm, 10.26 mm, 12.81 mm, and 134.68 mm in males, respectively. There were statistically significantly differences in the frontal horn width, third (3rd) ventricle width, and the maximum transverse inner diameter of the skull values in between sexes. The mean values of Evans' index which obtanied with maximum width between the frontal horns of the lateral ventricles divided by the maximum transverse inner diameter of the skull were found as 0.280 ±0.172 in females; whereas the same dimensions were calculated 0.276±0.161 in males. These values were lower in healthy male subjects than females, however; there were no found significantly difference between groups. Present findings obtained from MRI are necessary anatomical baseline data for interpreting pathological changes, planning surgery, and determining presence and progress of some neurological diseases.

Morphometric assessment of the external anatomy of fourth ventricle & dorsal brainstem in South Indian population

“…Patnaik P et al, 14 obtanied with maximum width between the frontal horns of the lateral ventricles divided by the maximum transverse inner diameter of the skull were found as 0.280 ±0.172 in females; whereas the same dimensions were calculated 0.276±0.161 in males. These values were lower in healthy male subjects than females, however; there were no found significantly difference between groups.…”

Predictive Value of the Third Ventricle Width for Neurological Status in Multiple Sclerosis

“…The median value of 3VW was 5.5 mm (25–75th percentiles, 3.8–7.4; range, 1.1–13.5). When compared, 3VW measured in patients with MS in this study with age-dependent normal values obtained with similar methodology [ 25 ], taking the mean ± 1.5 SD as a normal range, 3VW was enlarged in 43 patients (46%).…”

“…When adopting age-dependent normal values of 3VW [ 25 ], in the CI subgroup, 74% of patients had the third ventricle enlarged and 26% had 3VW within normal range, whereas within CP subjects, 37% had enlargement of the third ventricle and 63% had 3VW within normal range ( p = 0.003) ( Figure 2 A). EDSS was also higher in subjects with enlargement of the third ventricle ( p = 0.04) ( Figure 2 B).…”

“…However, the predictive value of this parameter for the neurological status of patients with MS must first be confirmed. Data on age-dependent normal values of 3VW are available [ 25 , 29 ]. According to these data, 46% of patients with MS in this study had an enlarged third ventricle.…”

Comparison of morphometric parameters in prediction of hydrocephalus using random forests

“…ER was described by Evans [10] in 1942 as a method of measurement of ventricular size in pediatric patients. Current guidelines state that an ER greater than 0.3 indicates hydrocephalus [5,11,12].…”