The objective of this work was to study the epidemiological profile of maternal deaths at the Forécariah prefectural hospital from January 1, 2016 to December 31, 2020. Methodology: this was a descriptive, cross-sectional study with retrospective collection, including women who died before, during or within 42 days after childbirth. Sociodemographic and clinical variables, circumstances and causes of death as well as the process of maternal death reviews (MDR) were studied. The data were analyzed using EPI Info version 7.2 6 software. Central tendency parameters (mean, standard deviation), relative and absolute frequencies were reported. Results: The maternal mortality ratio was 348 deaths per 100,000 live births. The average age was 31 ±5.65 years. The majority of deceased women were unemployed (67.69%), most of them married (72.31%), and multiparous in 33.85% of cases. Hemorrhages during delivery constituted 52.72% of the direct causes. The effectiveness of reviews of maternal deaths was 10.77% and deaths deemed avoidable represented 98.46%, mainly linked to the 3rd delay in 58.46% of cases. Conclusion: achieving the goal of sustainable development (SDG 3.1) requires community participation, reorganization of the health system and government involvement.