Mortality after osteoporotic fractures

Abstract

The aim of this study was to examine the pattern of mortality following osteoporotic fractures at the spine, shoulder, hip, and forearm. We studied 2,847 patients with fractures at these sites identified from the radiology department in Malmö, Sweden. Poisson regression was used to compute mortality immediately after the fracture and with time. Mortality immediately after fracture was significantly higher in fracture cases than in the general population except for forearm fractures in both men and women. Mortality was higher in men than in women, but not different when adjusted for sex-specific population risks. For spine, shoulder, and hip fracture, mortality fell after the 1st year, an effect that was most marked for patients with spine fractures. The decrease in mortality risk with time was significant for hip, vertebral, and shoulder fracture. We conclude that the risk of death is increased in patients with osteoporotic fractures and that the highest risk is found immediately after the fracture event. The decreasing mortality with time after fracture may be due in part to a decrease in deaths causally related to the fracture. The extent to which early intervention for osteoporosis might avoid some of these deaths is unknown.

Nutritional status, as determined by the Mini-Nutritional Assessment, and osteoporosis: a cross-sectional study of an elderly female population

“…Many patients with osteoporotic hip fractures have previously been found to be undernourished and suffering from proteinenergy malnutrition (PEM) (Ponzer et al, 1999). Osteoporosis is also a predictor of mortality (Johnell et al, 2004) and, likewise, the MNA has been found to predict mortality in geriatric patients both during short-term stays in the hospital (Van Nes et al, 2001) and during a long-term 3-year followup (Persson et al, 2002).…”

Undiagnosed Vertebral Fractures Influence Quality of Life in Postmenopausal Women With Reduced Ultrasound Parameters

“…Several other studies have shown that in postmenopausal women the consequences of vertebral fractures are markedly influenced by the number and severity of prior vertebral fractures [7,27]. It has been reported that patients with multiple fractures are at increased risk of morbidity and mortality [2,14]. Therefore, the recognition of vertebral fractures is critical for the prediction of possible future fractures.…”

Health economics of osteoporosis

“…Studies have shown that wrist fractures are associated with some costs and quality of life reductions the first year after fracture [23][24][25][26]. Wrist fractures have not been indicated to increase mortality compared to the general population [27][28][29]. The incidence of fracture increases linearly with age (see Figure 1).…”

“…Hip and vertebral mortality rates in the first and following years after fracture event were derived from different published sources [27,128,130], respectively. In the raloxifene, study a relative risk of mortality after clinical vertebral fractures estimated at 2.5 the year after fracture and 1.3 in subsequent years for all ages was used.…”